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Details on Person UniProt:P37288 AVPR1A
| Class:Id | ReferenceGeneProduct:67064 |
|---|---|
| _chainChangeLog | chain:1-418 added on Sat February 7 2015 |
| _displayName | UniProt:P37288 AVPR1A |
| _timestamp | 2024-11-03 19:44:10 |
| chain | chain:1-418 |
| checksum | 477D4260EC826561 |
| comment | FUNCTION Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.INTERACTION Differences in regional receptor expression in the brain as well as differences in social behavior may result from a highly variable repetitive sequence in the 5' flanking region of AVPR1A. One such allelic variant has been linked to autism.SIMILARITY Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. |
| description | recommendedName: Vasopressin V1a receptor shortName: V1aR alternativeName: AVPR V1a alternativeName: Antidiuretic hormone receptor 1a alternativeName: Vascular/hepatic-type arginine vasopressin receptor |
| geneName | AVPR1A AVPR1 |
| identifier | P37288 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Proteomics identification Receptor Reference proteome Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | AVPR1A |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8998086] ENSEMBL:ENSG00000166148 AVPR1A [Homo sapiens] |
| secondaryIdentifier | V1AR_HUMAN |
| sequenceLength | 418 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:388484] AVPR1A [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P37288 AVPR1A (67064)
