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Details on Person UniProt:O43396 TXNL1
| Class:Id | ReferenceGeneProduct:66601 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Sat February 7 2015;chain:2-289 added on Sat February 7 2015;initiator methionine:1 for 66601 removed on Fri Nov 03 2023;initiator methionine: for 66601 added on Fri Nov 03 2023;initiator methionine: for 66601 removed on Fri Aug 15 2025;initiator methionine:1 for 66601 added on Fri Aug 15 2025 |
| _displayName | UniProt:O43396 TXNL1 |
| _timestamp | 2025-08-15 21:35:02 |
| chain | initiator methionine:1 chain:2-289 |
| checksum | B2CC0BD8042225C2 |
| comment | FUNCTION Active thioredoxin with a redox potential of about -250 mV.SUBUNIT Component of the 19S regulatory cap of the 26S proteasome. Interacts with PSMD14/RPN11. Interacts with, and reduces EEF1A1.SUBCELLULAR LOCATION At least 85% of the cellular TXNL1 is proteasome-associated.TISSUE SPECIFICITY Ubiquitous. |
| description | recommendedName: Thioredoxin-like protein 1 alternativeName: 32 kDa thioredoxin-related protein |
| geneName | TXNL1 TRP32 TXL TXNL |
| identifier | O43396 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cytoplasm Direct protein sequencing Disulfide bond Electron transport Nucleus Phosphoprotein Proteasome Proteomics identification Redox-active center Reference proteome Transport |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | TXNL1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8990476] ENSEMBL:ENSG00000091164 TXNL1 [Homo sapiens] |
| secondaryIdentifier | TXNL1_HUMAN |
| sequenceLength | 289 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:9715138] TXNL1 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:O43396 TXNL1 (66601)
