Query author contributions in Reactome
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Details on Person UniProt:P34981 TRHR
| Class:Id | ReferenceGeneProduct:66405 |
|---|---|
| _chainChangeLog | chain:1-398 added on Fri February 6 2015 |
| _displayName | UniProt:P34981 TRHR |
| _timestamp | 2026-02-20 22:39:26 |
| chain | chain:1-398 |
| checksum | FE920B5F2E933D3E |
| comment | FUNCTION Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.INTERACTION The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the G-protein coupled receptor 1 family. |
| description | recommendedName: Thyrotropin-releasing hormone receptor shortName: TRH-R alternativeName: Thyroliberin receptor |
| geneName | TRHR |
| identifier | P34981 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Congenital hypothyroidism Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Membrane Proteomics identification Receptor Reference proteome Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | TRHR |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8995200] ENSEMBL:ENSG00000174417 TRHR [Homo sapiens] |
| secondaryIdentifier | TRFR_HUMAN Q2M339 |
| sequenceLength | 398 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:444556] TRHR [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P34981 TRHR (66405)
