Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q9Y2L5 TRAPPC8
| Class:Id | ReferenceGeneProduct:66367 |
|---|---|
| _chainChangeLog | chain:1-1435 added on Fri February 6 2015 |
| _displayName | UniProt:Q9Y2L5 TRAPPC8 |
| _timestamp | 2026-02-20 21:35:36 |
| chain | chain:1-1435 |
| checksum | A6D60A7C9E65F46D |
| comment | FUNCTION Plays a role in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage (PubMed:21525244). Maintains together with TBC1D14 the cycling pool of ATG9 required for initiation of autophagy (PubMed:26711178). Involved in collagen secretion (PubMed:32095531).SUBUNIT Component of the multisubunit TRAPP (transport protein particle) complex, which includes TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12 (PubMed:11805826, PubMed:21525244). Interacts with TBC1D14 (PubMed:26711178). Interacts (via C-terminus) with TMEM131 (via C-terminus); the interaction is direct and is involved in collagen secretion (PubMed:32095531).SUBCELLULAR LOCATION May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.SIMILARITY Belongs to the TRS85 family.SEQUENCE CAUTION Truncated N-terminus.SEQUENCE CAUTION Truncated N-terminus.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Truncated N-terminus. |
| description | recommendedName: Trafficking protein particle complex subunit 8 alternativeName: Protein TRS85 homolog |
| geneName | TRAPPC8 KIAA1012 |
| identifier | Q9Y2L5 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing ER-Golgi transport Golgi apparatus Phosphoprotein Proteomics identification Reference proteome Transport |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | TRAPPC8 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962330] ENSEMBL:ENSG00000153339 TRAPPC8 [Homo sapiens] |
| secondaryIdentifier | TPPC8_HUMAN A0JP15 B3KME5 Q9H0L2 |
| sequenceLength | 1435 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:155150] UniProt:Q9Y2L5-2 TRAPPC8 [Homo sapiens] [ReferenceIsoform:415960] UniProt:Q9Y2L5-1 TRAPPC8 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:5683768] TRAPPC8 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9Y2L5 TRAPPC8 (66367)
