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Details on Person UniProt:O75347 TBCA
| Class:Id | ReferenceGeneProduct:65701 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Fri February 6 2015;chain:2-108 added on Fri February 6 2015;initiator methionine:1 for 65701 removed on Fri Nov 03 2023;initiator methionine: for 65701 added on Fri Nov 03 2023;initiator methionine: for 65701 removed on Fri Aug 15 2025;initiator methionine:1 for 65701 added on Fri Aug 15 2025 |
| _displayName | UniProt:O75347 TBCA |
| _timestamp | 2025-08-15 22:04:48 |
| chain | initiator methionine:1 chain:2-108 |
| checksum | 222D8D945A5CD162 |
| comment | FUNCTION Tubulin-folding protein; involved in the early step of the tubulin folding pathway.SUBUNIT Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.INTERACTION Belongs to the TBCA family. |
| description | recommendedName: Tubulin-specific chaperone A alternativeName: TCP1-chaperonin cofactor A alternativeName: Tubulin-folding cofactor A shortName: CFA |
| geneName | TBCA |
| identifier | O75347 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Alternative splicing Chaperone Cytoplasm Cytoskeleton Microtubule Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | TBCA |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8961094] ENSEMBL:ENSG00000171530 TBCA [Homo sapiens] |
| secondaryIdentifier | TBCA_HUMAN B4DT30 |
| sequenceLength | 108 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8970767] UniProt:O75347-1 TBCA [Homo sapiens] [ReferenceIsoform:8970768] UniProt:O75347-2 TBCA [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:379538] TBCA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:8961266] TBCA [extracellular region] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:O75347 TBCA (65701)
