Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q15544 TAF11
| Class:Id | ReferenceGeneProduct:65554 |
|---|---|
| _chainChangeLog | chain:1-211 added on Fri February 6 2015 |
| _displayName | UniProt:Q15544 TAF11 |
| _timestamp | 2024-11-03 20:03:30 |
| chain | chain:1-211 |
| checksum | 77C7BDC667D19A8F |
| comment | FUNCTION The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473). TAF11, together with TAF13 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes (PubMed:33795473).SUBUNIT Component of the TFIID basal transcription factor complex, composed of TATA-box-binding protein TBP, and a number of TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473). Interacts with TAF13 both in vitro and intracellularly; also interacts directly with TBP (PubMed:9695952).INTERACTION TBP and TAFII18 bind to distinct domains of TAFII28.SIMILARITY Belongs to the TAF11 family. |
| description | recommendedName: Transcription initiation factor TFIID subunit 11 alternativeName: TFIID subunit p30-beta alternativeName: Transcription initiation factor TFIID 28 kDa subunit shortName: TAF(II)28 shortName: TAFII-28 shortName: TAFII28 |
| geneName | TAF11 TAF2I PRO2134 |
| identifier | Q15544 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Alternative splicing Direct protein sequencing Nucleus Proteomics identification Reference proteome Transcription Transcription regulation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | TAF11 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8998035] ENSEMBL:ENSG00000064995 TAF11 [Homo sapiens] |
| secondaryIdentifier | TAF11_HUMAN B2R8R3 B4DY18 Q9UHS0 |
| sequenceLength | 211 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8978069] UniProt:Q15544-1 TAF11 [Homo sapiens] [ReferenceIsoform:8978070] UniProt:Q15544-2 TAF11 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:65553] TAF11 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q15544 TAF11 (65554)
