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Details on Person UniProt:P80162 CXCL6
| Class:Id | ReferenceGeneProduct:65482 |
|---|---|
| _chainChangeLog | signal peptide:1-37 added on Fri February 6 2015;chain:38-114 added on Fri February 6 2015;chain:40-114 added on Fri February 6 2015;chain:43-114 added on Fri February 6 2015;chain:46-114 added on Fri February 6 2015 |
| _displayName | UniProt:P80162 CXCL6 |
| _timestamp | 2025-08-15 21:52:14 |
| chain | signal peptide:1-37 chain:38-114 chain:40-114 chain:43-114 chain:46-114 |
| checksum | 5A58B38C17F25178 |
| comment | FUNCTION Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).INTERACTION Belongs to the intercrine alpha (chemokine CxC) family.ONLINE INFORMATION CXCL6 entry |
| description | recommendedName: C-X-C motif chemokine 6 alternativeName: Chemokine alpha 3 shortName: CKA-3 alternativeName: Granulocyte chemotactic protein 2 shortName: GCP-2 alternativeName: Small-inducible cytokine B6 component recommendedName: Small-inducible cytokine B6, N-processed variant 1 /component component recommendedName: Small-inducible cytokine B6, N-processed variant 2 /component component recommendedName: Small-inducible cytokine B6, N-processed variant 3 /component |
| geneName | CXCL6 GCP2 SCYB6 |
| identifier | P80162 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Antibiotic Antimicrobial Chemotaxis Cytokine Direct protein sequencing Disulfide bond Heparin-binding Proteomics identification Reference proteome Secreted Signal |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | CXCL6 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8991799] ENSEMBL:ENSG00000124875 CXCL6 [Homo sapiens] |
| secondaryIdentifier | CXCL6_HUMAN B2R4X3 Q4W5D4 |
| sequenceLength | 114 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:373784] CXCL6(38-114) [extracellular region] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:P80162 CXCL6 (65482)
