Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q9UNK0 STX8
| Class:Id | ReferenceGeneProduct:65256 |
|---|---|
| _chainChangeLog | chain:1-236 added on Fri February 6 2015 |
| _displayName | UniProt:Q9UNK0 STX8 |
| _timestamp | 2024-11-03 20:21:39 |
| chain | chain:1-236 |
| checksum | 1E64A0DA77584CC4 |
| comment | FUNCTION Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.SUBUNIT Forms a SNARE complex with STX7, VTI1B and VAMP8 which functions in the homotypic fusion of late endosomes. Part of the SNARE core complex containing STX7, VAMP8 and VTI1B. Interacts with VAMP8 (By similarity). Interacts with HECTD3 (By similarity). Interacts with TPC1 (By similarity).INTERACTION Preferentially associated with the early endosome. To a lesser extent, also present in late endosome, the plasma membrane and coated pits (By similarity).TISSUE SPECIFICITY Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas.PTM Ubiquitinated by HECTD3.SIMILARITY Belongs to the syntaxin family. |
| description | recommendedName: Syntaxin-8 |
| geneName | STX8 |
| identifier | Q9UNK0 |
| isSequenceChanged | FALSE |
| keyword | Coiled coil Membrane Phosphoprotein Proteomics identification Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | STX8 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8989247] ENSEMBL:ENSG00000170310 STX8 [Homo sapiens] |
| secondaryIdentifier | STX8_HUMAN O60712 Q53XT8 |
| sequenceLength | 236 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:181548] STX8 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:376346] STX8 [lysosomal membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9UNK0 STX8 (65256)
