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Details on Person UniProt:P34741 SDC2

Class:Id	ReferenceGeneProduct:64230
_chainChangeLog	signal peptide:1-18 added on Sat February 7 2015;chain:19-201 added on Sat February 7 2015
_displayName	UniProt:P34741 SDC2
_timestamp	2024-11-03 20:07:39
chain	signal peptide:1-18 chain:19-201
checksum	7DA4159D54741054
comment	FUNCTION Cell surface proteoglycan which regulates dendritic arbor morphogenesis.SUBUNIT Interacts (via cytoplasmic domain) with SARM1 (By similarity). Forms a complex with SDCBP and PDCD6IP (PubMed:22660413).INTERACTION O-glycosylated with core 1 or possibly core 8 glycans. Contains heparan sulfate (PubMed:22171320). Also contains chondroitin sulfate (By similarity).SIMILARITY Belongs to the syndecan proteoglycan family.SEQUENCE CAUTION Extended N-terminus.
description	recommendedName: Syndecan-2 shortName: SYND2 alternativeName: Fibroglycan alternativeName: Heparan sulfate proteoglycan core protein shortName: HSPG cdAntigenNameCD362/cdAntigenName
geneName	SDC2 HSPG1
identifier	P34741
isSequenceChanged	FALSE
keyword	3D-structure Differentiation Glycoprotein Heparan sulfate Membrane Neurogenesis Phosphoprotein Proteoglycan Proteomics identification Reference proteome Signal Transmembrane Transmembrane helix
modified	[InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
name	SDC2
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:9002049] ENSEMBL:ENSG00000169439 SDC2 [Homo sapiens]
secondaryIdentifier	SDC2_HUMAN B3KQA3 Q6PIS6 Q9H6V1
sequenceLength	201
species	[Species:48887] Homo sapiens
(referenceEntity)	[EntityWithAccessionedSequence:190315] SDC2 [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:2054101] SDC2 [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:2063988] Gal-Gal-Xyl-SDC2 [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:2063997] GlcA-Gal-Gal-Xyl-SDC2 [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:2064109] XylS-SDC2 [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:2064132] Gal-Xyl-SDC2 [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:2076320] HS(5)-SDC2 [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:2076356] HS(4)-SDC2 [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:2076361] Heparan(3)-SDC2 [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:2076397] Heparan(2)-SDC2 [Golgi lumen] [Homo sapiens] List all 30 refering instances
(referenceSequence)	[GroupModifiedResidue:2063956] O-xylosyl-L-serine (O3-(β-D-galactosyl-(1→3)-β-D-galactosyl-(1→4)-β-D-xylosyl)-L-serine residue) at unknown position [ModifiedResidue:2064070] O-xylosyl-L-serine at unknown position [GroupModifiedResidue:2064152] O-xylosyl-L-serine (O3-(4-β-D-galactosyl-β-D-xylosyl)-L-serine residue) at unknown position [GroupModifiedResidue:2064212] O-xylosyl-L-serine (3-O-(β-D-glucuronosyl-(1→3)-β-D-galactosyl-(1→3)-β-D-galactosyl-(1→4)-β-D-xylosyl)-L-serine residue) at unknown position [GroupModifiedResidue:2076331] O-xylosyl-L-serine (ChEBI:63646) at unknown position [GroupModifiedResidue:2076382] O-xylosyl-L-serine (ChEBI:63657) at unknown position [GroupModifiedResidue:2076403] O-xylosyl-L-serine (ChEBI:63648) at unknown position [GroupModifiedResidue:2076421] O-xylosyl-L-serine (ChEBI:63652) at unknown position [GroupModifiedResidue:2076422] O-xylosyl-L-serine (ChEBI:63653) at unknown position [GroupModifiedResidue:2076432] O-xylosyl-L-serine (ChEBI:63645) at unknown position List all 19 refering instances
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No pathways have been reviewed or authored by UniProt:P34741 SDC2 (64230)