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Query author contributions in Reactome

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Details on Person UniProt:Q9NSD7 RXFP3

Class:IdReferenceGeneProduct:64132
_chainChangeLogchain:1-469 added on Fri February 6 2015
_displayNameUniProt:Q9NSD7 RXFP3
_timestamp2026-02-20 22:37:35
chainchain:1-469
checksum932E7B3001689F7B
commentFUNCTION Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.SUBCELLULAR LOCATION Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.SIMILARITY Belongs to the G-protein coupled receptor 1 family.
descriptionrecommendedName: Relaxin-3 receptor 1 shortName: RLN3 receptor 1 alternativeName: G protein-coupled receptor SALPR alternativeName: G-protein coupled receptor GPCR135 alternativeName: Relaxin family peptide receptor 3 alternativeName: Somatostatin- and angiotensin-like peptide receptor
geneNameRXFP3
GPCR135
RLN3R1
SALPR
identifierQ9NSD7
isSequenceChangedFALSE
keyword3D-structure
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Membrane
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix
modified[InstanceEdit:84067] Schmidt, EE, 2003-12-18 04:29:09
[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:8987656] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9688885] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
nameRXFP3
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9000279] ENSEMBL:ENSG00000182631 RXFP3 [Homo sapiens]
secondaryIdentifierRL3R1_HUMAN
Q14DA5
sequenceLength469
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:444841] RXFP3 [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q9NSD7 RXFP3 (64132)