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Details on Person UniProt:P82930 MRPS34
| Class:Id | ReferenceGeneProduct:63828 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Fri February 6 2015;chain:2-218 added on Fri February 6 2015 |
| _displayName | UniProt:P82930 MRPS34 |
| _timestamp | 2024-11-03 20:16:28 |
| chain | chain:1-218 |
| checksum | 58DC48FF63276060 |
| comment | FUNCTION Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation.SUBUNIT Component of the mitochondrial small ribosomal subunit (mt-SSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.SUBCELLULAR LOCATION The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the mitochondrion-specific ribosomal protein mS34 family. |
| description | recommendedName: fullName evidence="5"Small ribosomal subunit protein mS34 alternativeName: 28S ribosomal protein S34, mitochondrial shortName: MRP-S34 shortName: S34mt |
| geneName | MRPS34 |
| identifier | P82930 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Disease variant Mitochondrion Primary mitochondrial disease Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | MRPS34 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8988089] ENSEMBL:ENSG00000074071 MRPS34 [Homo sapiens] |
| secondaryIdentifier | RT34_HUMAN Q9BVI7 |
| sequenceLength | 218 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5368186] MRPS34 [mitochondrial inner membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P82930 MRPS34 (63828)
