Query author contributions in Reactome
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Details on Person UniProt:P49247 RPIA
| Class:Id | ReferenceGeneProduct:63548 |
|---|---|
| _chainChangeLog | chain:1-311 added on Fri February 6 2015 |
| _displayName | UniProt:P49247 RPIA |
| _timestamp | 2024-11-03 20:02:57 |
| chain | chain:1-311 |
| checksum | 4ED587A40F10223D |
| comment | FUNCTION Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate and participates in the first step of the non-oxidative branch of the pentose phosphate pathway.CATALYTIC ACTIVITY aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphatePATHWAY Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.INTERACTION The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the ribose 5-phosphate isomerase family. |
| description | recommendedName: fullName evidence="3"Ribose-5-phosphate isomerase ecNumber evidence="2"5.3.1.6 alternativeName: Phosphoriboisomerase |
| geneName | RPIA RPI |
| identifier | P49247 |
| isSequenceChanged | FALSE |
| keyword | Disease variant Isomerase Methylation Neuropathy Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | RPIA |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8996230] ENSEMBL:ENSG00000153574 RPIA [Homo sapiens] |
| secondaryIdentifier | RPIA_HUMAN Q541P9 Q96BJ6 |
| sequenceLength | 311 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:71304] RPIA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:5660009] RPIA A61V [cytosol] [Homo sapiens] |
| (referenceSequence) | [ReplacedResidue:5660011] L-alanine 61 replaced with L-valine |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P49247 RPIA (63548)
