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Details on Person UniProt:P09001 MRPL3
| Class:Id | ReferenceGeneProduct:63307 |
|---|---|
| _chainChangeLog | chain:1-348 added on Sat February 7 2015;chain:1-348 removed on Fri February 17 2017;transit peptide:1-40 added on Fri February 17 2017;chain:41-348 added on Fri February 17 2017 |
| _displayName | UniProt:P09001 MRPL3 |
| _timestamp | 2024-11-03 20:21:08 |
| chain | transit peptide:1-40 chain:41-348 |
| checksum | 6DE6B5BD6BD72E32 |
| comment | SUBUNIT Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:25278503, PubMed:25838379, PubMed:28892042, PubMed:35177605). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.SUBCELLULAR LOCATION The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the universal ribosomal protein uL3 family. |
| description | recommendedName: fullName evidence="6"Large ribosomal subunit protein uL3m alternativeName: 39S ribosomal protein L3, mitochondrial shortName: L3mt shortName: MRP-L3 |
| geneName | MRPL3 MRL3 RPML3 |
| identifier | P09001 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Disease variant Mitochondrion Primary mitochondrial disease Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein Transit peptide |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | MRPL3 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8999733] ENSEMBL:ENSG00000114686 MRPL3 [Homo sapiens] |
| secondaryIdentifier | RM03_HUMAN Q6IBT2 |
| sequenceLength | 348 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5368242] MRPL3 [mitochondrial inner membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P09001 MRPL3 (63307)
