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Details on Person STAT1 [cytosol]

Class:Id	EntityWithAccessionedSequence:629622
_displayName	STAT1 [cytosol]
_timestamp	2016-12-02 13:38:23
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:629624] Garapati, P V, 2010-04-26
endCoordinate	750
modified	[InstanceEdit:8951035] Duenas, Corina, 2016-12-02
name	STAT1 Signal transducer and activator of transcription 1-alpha/beta STAT1_HUMAN
referenceEntity	[ReferenceGeneProduct:404006] UniProt:P42224 STAT1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1110469] R-HSA-629622.2
startCoordinate	2
(activeUnit)	[NegativeRegulation:9008011] Negative regulation by 'RUNX2:STAT1 [cytosol]'
(hasComponent)	[Complex:8950267] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] [Homo sapiens] [Complex:8950779] STAT1:STAT3:IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2 [plasma membrane] [Homo sapiens] [Complex:8952787] STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] [Homo sapiens] [Complex:8983842] IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] [Homo sapiens] [Complex:8983998] IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] [Homo sapiens] [Complex:8985934] IL9:p-Y407-IL9R:p-JAK1:IL2RG:p-904,939-JAK3:STAT1 [plasma membrane] [Homo sapiens] [Complex:8987073] IL24:IL22RA1:p-JAK1:IL20RB:STAT1 [plasma membrane] [Homo sapiens] [Complex:9008005] RUNX2:STAT1 [cytosol] [Homo sapiens]
(hasMember)	[DefinedSet:380756] STAT family members [cytosol] [Homo sapiens] [DefinedSet:1112559] STAT1, STAT3 [cytosol] [Homo sapiens] [CandidateSet:1169379] ISG15 targets [cytosol] [Homo sapiens] [DefinedSet:1433551] STATs [cytosol] [Homo sapiens] [DefinedSet:6788573] STAT1,STAT3,STAT6 [cytosol] [Homo sapiens] [DefinedSet:6790032] STAT3-upregulated cytosolic proteins [cytosol] [Homo sapiens] [DefinedSet:8962899] Proteins overexpressed after IL27 stimulation [cytosol] [Homo sapiens] [DefinedSet:9006868] STAT1,STAT3,STAT4,STAT5 [cytosol] [Homo sapiens] [DefinedSet:9009216] STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] [Homo sapiens] [DefinedSet:9010176] STAT1, STAT3, STAT5 [cytosol] [Homo sapiens] List all 12 refering instances
(input)	[BlackBoxEvent:8950518] STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex [Homo sapiens] [BlackBoxEvent:8952786] STAT1 binds active IL6ST:IL12RB2 heterodimer [Homo sapiens] [BlackBoxEvent:8983841] STAT1 associates with IL6ST:IL6ST [Homo sapiens] [BlackBoxEvent:8983996] STAT1 and STAT4 associate with IL12RB2:IL6ST receptor [Homo sapiens] [BlackBoxEvent:8984021] STAT1,STAT3 associate with IL27RA:IL12RB2 receptor [Homo sapiens] [BlackBoxEvent:8985991] STAT1 binds IL9:p-Y407-IL9R:p-JAK1:IL2RG:p-904,939-JAK3 complex [Homo sapiens] [BlackBoxEvent:8987158] IL24:IL22RA1:p‑JAK1:IL20RB binds STAT1 [Homo sapiens] [Reaction:9008015] RUNX2 binds STAT1 [Homo sapiens] [BlackBoxEvent:9865511] Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9896374] Update Tracker - [EntityWithAccessionedSequence:629622] STAT1 [cytosol] - v60:[modifyStartCoordinate]
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No pathways have been reviewed or authored by STAT1 [cytosol] (629622)