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Details on Person Activation of highly calcium permeable nicotinic acetylcholine receptors

Class:IdReaction:622326
_displayNameActivation of highly calcium permeable nicotinic acetylcholine receptors
_doReleaseTRUE
_timestamp2020-03-13 17:28:08
authored[InstanceEdit:629591] Mahajan, SS, 2010-04-26
catalystActivity[CatalystActivity:629585] ligand-gated monoatomic ion channel activity of 0-acteylcholine bound to calcium permeable nictonic acteylcholine receptor complex [plasma membrane]
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
[Compartment:70101] cytosol
created[InstanceEdit:622324] Mahajan, SS, 2010-04-22
edited[InstanceEdit:749480] Gillespie, ME, 2010-05-18
[InstanceEdit:9609387] Orlic-Milacic, Marija, 2018-05-23
input[SimpleEntity:74112] Ca2+ [extracellular region]
isChimericFALSE
literatureReference[LiteratureReference:548997] Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine
[LiteratureReference:633822] Fractional Ca(2+) current through human neuronal alpha7 nicotinic acetylcholine receptors
modified[InstanceEdit:629606] Mahajan, SS, 2010-04-26
[InstanceEdit:629619] Mahajan, SS, 2010-04-26
[InstanceEdit:633876] Mahajan, SS, 2010-04-29
[InstanceEdit:790240] Mahajan, SS, 2010-05-24
[InstanceEdit:790916] Mahajan, SS, 2010-05-24
[InstanceEdit:791484] Mahajan, SS, 2010-05-24
[InstanceEdit:9609383] Orlic-Milacic, Marija, 2018-05-23
[InstanceEdit:9609388] Orlic-Milacic, Marija, 2018-05-23
[InstanceEdit:9678183] Gillespie, Marc E, 2020-03-13
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActivation of highly calcium permeable nicotinic acetylcholine receptors
output[SimpleEntity:74016] Ca2+ [cytosol]
precedingEvent
releaseDate2010-06-15
reviewed[InstanceEdit:386898] Restituito, S, 2008-11-27 12:38:49
[InstanceEdit:9674802] Wen, Hua, 2020-01-24
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105044] R-HSA-622326.4
summation[Summation:633843] Nicotinic acetylcholine receptors are activated upon ligand ...
(hasEvent)[Pathway:629597] Highly calcium permeable nicotinic acetylcholine receptors [Homo sapiens]
(updatedInstance)[_UpdateTracker:9779054] Update Tracker - [Reaction:622326] Activation of highly calcium permeable nicotinic acetylcholine receptors - v66:[removeInput, removeOutput]
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