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Details on Person IL35 [extracellular region]

Class:IdComplex:622267
_displayNameIL35 [extracellular region]
_timestamp2017-03-30 13:07:10
compartment[Compartment:984] extracellular region
created[InstanceEdit:622266] Jupe, S, 2010-04-22
hasComponent
isChimericFALSE
literatureReference[LiteratureReference:8949818] Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin
[LiteratureReference:8949825] Low Serum Levels of Interleukin 35 in Patients with Rheumatoid Arthritis
modified[InstanceEdit:622268] Jupe, S, 2010-04-22
[InstanceEdit:8949823] Jupe, Steve, 2016-11-29
[InstanceEdit:8983874] Varusai, Thawfeek, 2017-03-30
nameIL35
Interleukin-35
IL12A:EBI3
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6811924] R-HSA-622267.3
summation[Summation:8949826] Interleukin-35 can be secreted(PMID: 9342359) and be detecte...
(hasComponent)[Complex:6809138] IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] [Homo sapiens]
[Complex:8950255] IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] [Homo sapiens]
[Complex:8951140] IL12A:EBI3:IL27RA:JAK2:IL12RB2:JAK2 [plasma membrane] [Homo sapiens]
[Complex:8951177] IL12A:EBI3:IL12RB2:IL27RA [plasma membrane] [Mus musculus]
[Complex:8951178] IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] [Homo sapiens]
[Complex:8983520] IL35:(IL12RB2:JAK2 dimer) [plasma membrane] [Homo sapiens]
[Complex:8983525] IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] [Homo sapiens]
[Complex:8983843] IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] [Homo sapiens]
[Complex:8983873] IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] [Homo sapiens]
[Complex:8983989] IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] [Homo sapiens]
List all 12 refering instances
(input)[BlackBoxEvent:6809140] IL35 binds IL-12RB2:IL6ST receptor [Homo sapiens]
[BlackBoxEvent:8983518] IL35 binds IL6ST:IL6ST receptor [Homo sapiens]
[BlackBoxEvent:8983519] IL35 binds IL12RB2:IL12RB2 receptor [Homo sapiens]
[BlackBoxEvent:8984001] IL35 binds IL27RA:IL12RB2 receptor [Homo sapiens]
(output)[BlackBoxEvent:448627] Interleukin-35 translocates from the ER lumen to the extracellular region [Homo sapiens]
(updatedInstance)[_UpdateTracker:9896824] Update Tracker - [Complex:622267] IL35 [extracellular region] - v60:[addLiteratureReference, addName, addSummation]
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No pathways have been reviewed or authored by IL35 [extracellular region] (622267)