Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:P15259 PGAM2
| Class:Id | ReferenceGeneProduct:61884 |
|---|---|
| _chainChangeLog | chain:1-253 added on Fri February 6 2015 |
| _displayName | UniProt:P15259 PGAM2 |
| _timestamp | 2026-02-20 23:09:20 |
| chain | chain:1-253 |
| checksum | 0FDC97631104FCF7 |
| comment | FUNCTION Catalyzes the interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate, but with a reduced activity.CATALYTIC ACTIVITY (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerateCATALYTIC ACTIVITY (2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+)SUBUNIT Homodimer. Interacts with ENO1.INTERACTION Expressed in the heart and muscle. Not found in the liver and brain.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. |
| description | recommendedName: Phosphoglycerate mutase 2 ecNumber evidence="4"5.4.2.11 ecNumber evidence="4"5.4.2.4 alternativeName: BPG-dependent PGAM 2 alternativeName: Muscle-specific phosphoglycerate mutase alternativeName: Phosphoglycerate mutase isozyme M shortName: PGAM-M |
| geneName | PGAM2 PGAMM |
| identifier | P15259 |
| isSequenceChanged | FALSE |
| keyword | Disease variant Glycogen storage disease Glycolysis Hydrolase Isomerase Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | PGAM2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8993815] ENSEMBL:ENSG00000164708 PGAM2 [Homo sapiens] |
| secondaryIdentifier | PGAM2_HUMAN |
| sequenceLength | 253 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:70487] PGAM2 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P15259 PGAM2 (61884)
