Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person PDPK1 [plasma membrane]

Class:IdEntityWithAccessionedSequence:61459
_displayNamePDPK1 [plasma membrane]
_timestamp2013-05-28 19:19:30
compartment[Compartment:876] plasma membrane
endCoordinate556
modified[InstanceEdit:109694] de Bono, B, 2004-01-20 06:18:07
[InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08
[InstanceEdit:157501] de Bono, B, 2004-12-31 08:25:52
[InstanceEdit:437270] Jupe, S, 2009-09-14
[InstanceEdit:443026] Jupe, S, 2009-10-01
[InstanceEdit:2219539] Orlic-Milacic, M, 2012-05-01
[InstanceEdit:3632907] Wu, G, 2013-05-28
namePDPK1
PDK1
3-phosphoinositide dependent protein kinase-1
referenceEntity[ReferenceGeneProduct:61460] UniProt:O15530 PDPK1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:369758] R-HSA-61459.1
startCoordinate1
(activeUnit)[CatalystActivity:198343] protein serine/threonine kinase activity of p-S-AKT:PDPK1:PIP3 [plasma membrane]
[CatalystActivity:437273] 3-phosphoinositide-dependent protein kinase activity of PDPK1:PIP3:PRKCZ [plasma membrane]
[CatalystActivity:2243940] protein serine/threonine kinase activity of PDPK1:p-S473-AKT1 E17K mutant:PIP2 [plasma membrane]
(hasComponent)[Complex:109697] PDPK1:PIP3 [plasma membrane] [Homo sapiens]
[Complex:198338] PIP3:PDK1:active AKT [plasma membrane] [Homo sapiens]
[Complex:198360] PDK1:AKT:PIP3 [plasma membrane] [Homo sapiens]
[Complex:198618] PIP3:PDK1:Phospho-AKT [plasma membrane] [Homo sapiens]
[Complex:202311] PDK1:PIP2,PIP3 [plasma membrane] [Homo sapiens]
[Complex:377179] PDPK1:PIP3 [plasma membrane] [Homo sapiens]
[Complex:377408] PDK1:PIP3:Phospho S6K1 [plasma membrane] [Homo sapiens]
[Complex:2219520] PDPK1:PIP2 [plasma membrane] [Homo sapiens]
[Complex:9731042] PDPK1:M [plasma membrane] [Homo sapiens]
[Complex:9755778] N:M:PDPK1 [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:432180] AKT1/PDK1 [plasma membrane] [Homo sapiens]
(input)[Reaction:109701] PDPK1 binds PIP3 [Homo sapiens]
[Reaction:9731018] SARS-CoV-1 M binds to PDPK1 [Homo sapiens]
[Reaction:9755777] SARS-CoV-2 M, N bind to PDPK1 [Homo sapiens]
(physicalEntity)[CatalystActivity:377328] protein serine/threonine kinase activity of PDPK1 [plasma membrane]
(updatedInstance)[_UpdateTracker:9868225] Update Tracker - [EntityWithAccessionedSequence:61459] PDPK1 [plasma membrane] - v30:[modifyName]
[_UpdateTracker:9868410] Update Tracker - [EntityWithAccessionedSequence:61459] PDPK1 [plasma membrane] - v31:[modifyName]
[_UpdateTracker:9872626] Update Tracker - [EntityWithAccessionedSequence:61459] PDPK1 [plasma membrane] - v41:[modifyEndCoordinate]
[_UpdateTracker:9880992] Update Tracker - [EntityWithAccessionedSequence:61459] PDPK1 [plasma membrane] - v45:[addName]
[Change default viewing format]
No pathways have been reviewed or authored by PDPK1 [plasma membrane] (61459)
Follow Reactome