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Details on Person UniProt:P25105 PTAFR
| Class:Id | ReferenceGeneProduct:61264 |
|---|---|
| _chainChangeLog | chain:1-342 added on Fri February 6 2015 |
| _displayName | UniProt:P25105 PTAFR |
| _timestamp | 2024-11-03 19:42:57 |
| chain | chain:1-342 |
| checksum | 890073C9EBA79228 |
| comment | FUNCTION Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.SUBUNIT Interacts with ARRB1.INTERACTION Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes.INDUCTION By CSF2/GM-CSF, IL5/interleukin-5 and n-butyrate.SIMILARITY Belongs to the G-protein coupled receptor 1 family. |
| description | recommendedName: Platelet-activating factor receptor shortName: PAF-R shortName: PAFr |
| geneName | PTAFR PAFR |
| identifier | P25105 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Proteomics identification Receptor Reference proteome Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | PTAFR |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:6785050] ENSEMBL:ENSG00000169403 PTAFR [Homo sapiens] |
| secondaryIdentifier | PTAFR_HUMAN A3KMC8 A8K2H5 |
| sequenceLength | 342 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:419376] PTAFR [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:6804787] PTAFR [tertiary granule membrane] [Homo sapiens] [EntityWithAccessionedSequence:6804792] PTAFR [secretory granule membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P25105 PTAFR (61264)
