Query author contributions in Reactome
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Details on Person UniProt:O43482 OIP5
| Class:Id | ReferenceGeneProduct:60894 |
|---|---|
| _chainChangeLog | chain:1-229 added on Fri February 6 2015 |
| _displayName | UniProt:O43482 OIP5 |
| _timestamp | 2024-11-03 20:20:10 |
| chain | chain:1-229 |
| checksum | 0EBD4006193A3106 |
| comment | FUNCTION Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.SUBUNIT Homodimer, and heterodimer with MIS18A (PubMed:17199038, PubMed:26921242). Identified in a complex containing MIS18A, OIP5/MIS18B, MIS18BP1, RBBP7 and RBBP4 (PubMed:17199038). Binds outer membrane protein OpaP from Neisseria gonorrhoeae (in vitro) (PubMed:9466265).INTERACTION Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.SIMILARITY Belongs to the mis18 family. |
| description | recommendedName: Protein Mis18-beta alternativeName: Cancer/testis antigen 86 shortName: CT86 alternativeName: fullName evidence="5"Opa-interacting protein 5 shortName evidence="5"OIP-5 |
| geneName | OIP5 MIS18B |
| identifier | O43482 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell cycle Cell division Centromere Chromosome Metal-binding Mitosis Nucleus Phosphoprotein Proteomics identification Reference proteome Zinc |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | OIP5 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9001283] ENSEMBL:ENSG00000104147 OIP5 [Homo sapiens] |
| secondaryIdentifier | MS18B_HUMAN Q96BX7 |
| sequenceLength | 229 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:606286] OIP5 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:O43482 OIP5 (60894)
