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Details on Person UniProt:O95232 LUC7L3
| Class:Id | ReferenceGeneProduct:60794 |
|---|---|
| _chainChangeLog | chain:1-432 added on Sat February 7 2015 |
| _displayName | UniProt:O95232 LUC7L3 |
| _timestamp | 2024-11-03 19:41:39 |
| chain | chain:1-432 |
| checksum | E75F55EC0137310C |
| comment | FUNCTION Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing.SUBUNIT May interact with SFRS1 and form homodimers (PubMed:12565863). Interacts with JMJD6 (PubMed:19574390). Interacts with RBM25 (PubMed:18663000). Interacts with RSRC1 (via Arg/Ser-rich domain) (PubMed:15798186). Interacts with RRP1B (PubMed:23604122).INTERACTION The subnuclear localization is affected by cisplatin.ALTERNATIVE PRODUCTS Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung.PTM Phosphorylated in vitro by SRPK1, SRPK2 and CLK1.MISCELLANEOUS May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.SIMILARITY Belongs to the Luc7 family.SEQUENCE CAUTION Erroneous CDS prediction. |
| description | recommendedName: Luc7-like protein 3 alternativeName: Cisplatin resistance-associated-overexpressed protein alternativeName: Luc7A alternativeName: Okadaic acid-inducible phosphoprotein OA48-18 alternativeName: cAMP regulatory element-associated protein 1 shortName: CRE-associated protein 1 shortName: CREAP-1 |
| geneName | LUC7L3 CREAP1 CROP O48 |
| identifier | O95232 |
| isSequenceChanged | FALSE |
| keyword | Acetylation Alternative splicing Coiled coil DNA-binding Isopeptide bond mRNA processing mRNA splicing Nucleus Phosphoprotein Proteomics identification Reference proteome Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | LUC7L3 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8995511] ENSEMBL:ENSG00000108848 LUC7L3 [Homo sapiens] |
| secondaryIdentifier | LC7L3_HUMAN B3KN54 D3DTY1 Q6PHR9 Q9NUY0 Q9P2S7 |
| sequenceLength | 432 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:225580] UniProt:O95232-2 LUC7L3 [Homo sapiens] [ReferenceIsoform:402113] UniProt:O95232-1 LUC7L3 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:9770258] LUC7L3 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:O95232 LUC7L3 (60794)
