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Details on Person UniProt:P49146 NPY2R
| Class:Id | ReferenceGeneProduct:60666 |
|---|---|
| _chainChangeLog | chain:1-381 added on Sat February 7 2015 |
| _displayName | UniProt:P49146 NPY2R |
| _timestamp | 2024-11-03 20:02:11 |
| chain | chain:1-381 |
| checksum | 7D018C0169597BC7 |
| comment | FUNCTION Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.INTERACTION High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.SIMILARITY Belongs to the G-protein coupled receptor 1 family. |
| description | recommendedName: Neuropeptide Y receptor type 2 shortName: NPY2-R alternativeName: NPY-Y2 receptor shortName: Y2 receptor |
| geneName | NPY2R |
| identifier | P49146 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Proteomics identification Receptor Reference proteome Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | NPY2R |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8995571] ENSEMBL:ENSG00000185149 NPY2R [Homo sapiens] |
| secondaryIdentifier | NPY2R_HUMAN Q13281 Q13457 Q4W5G7 Q6AZZ6 Q9UE67 |
| sequenceLength | 381 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:388905] NPY2R [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P49146 NPY2R (60666)
