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Details on Person New CENPA-containing nucleosomes are deposited at the centromere

Class:IdBlackBoxEvent:606289
_displayNameNew CENPA-containing nucleosomes are deposited at the centromere
_doReleaseTRUE
_timestamp2014-11-02 09:36:41
authored[InstanceEdit:599714] May, B, 2010-04-15
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:606312] May, B, 2010-04-17
edited[InstanceEdit:599714] May, B, 2010-04-15
input[CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens]
[CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens]
[CandidateSet:181899] Histone H2A [nucleoplasm] [Homo sapiens]
[CandidateSet:181911] Histone H2B [nucleoplasm] [Homo sapiens]
[Complex:606282] CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA:H4 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:606332] Active establishment of centromeric CENP-A chromatin by RSF complex
[LiteratureReference:606283] Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP
[LiteratureReference:606307] HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres
[LiteratureReference:606290] HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres
[LiteratureReference:606344] Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1
[LiteratureReference:377688] The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres
[LiteratureReference:5633504] HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore
[LiteratureReference:5633519] Dual recognition of CENP-A nucleosomes is required for centromere assembly
modified[InstanceEdit:772522] May, B, 2010-05-21
[InstanceEdit:847691] May, B, 2010-05-30
[InstanceEdit:877409] May, B, 2010-06-14
[InstanceEdit:877423] May, B, 2010-06-14
[InstanceEdit:5252141] May, B, 2014-02-05
[InstanceEdit:5633525] May, Bruce, 2014-11-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNew CENPA-containing nucleosomes are deposited at the centromere
output[Complex:606328] CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA nucleosome [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2010-06-15
reviewed[InstanceEdit:847690] Almouzni-Pettinotti, G, Dunleavy, EM, 2010-05-30
[InstanceEdit:877422] Foltz, DR, 2010-06-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104659] R-HSA-606289.2
summation[Summation:606316] A new centromeric nucleosome containing histone H2A, histone...
(hasEvent)[Pathway:606279] Deposition of new CENPA-containing nucleosomes at the centromere [Homo sapiens]
(precedingEvent)[BlackBoxEvent:606287] RSF complex binds the centromere [Homo sapiens]
(updatedInstance)[_UpdateTracker:9785693] Update Tracker - [BlackBoxEvent:606289] New CENPA-containing nucleosomes are deposited at the centromere - v51:[addLiteratureReference]
[_UpdateTracker:9790221] Update Tracker - [BlackBoxEvent:606289] New CENPA-containing nucleosomes are deposited at the centromere - v34:[removeLiteratureReference]
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