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Details on Person UniProt:Q16718 NDUFA5
| Class:Id | ReferenceGeneProduct:60600 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Sat February 7 2015;chain:2-116 added on Sat February 7 2015;initiator methionine:1 for 60600 removed on Fri Nov 03 2023;initiator methionine: for 60600 added on Fri Nov 03 2023;initiator methionine: for 60600 removed on Fri Aug 15 2025;initiator methionine:1 for 60600 added on Fri Aug 15 2025 |
| _displayName | UniProt:Q16718 NDUFA5 |
| _timestamp | 2025-08-15 21:54:48 |
| chain | initiator methionine:1 chain:2-116 |
| checksum | 652339C1127E6F22 |
| comment | FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.SUBUNIT Complex I is composed of 45 different subunits.INTERACTION Expressed in all tissues examined with highest levels in heart, skeletal muscle and brain.SIMILARITY Belongs to the complex I NDUFA5 subunit family. |
| description | recommendedName: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 alternativeName: Complex I subunit B13 alternativeName: Complex I-13kD-B shortName: CI-13kD-B alternativeName: NADH-ubiquinone oxidoreductase 13 kDa-B subunit |
| geneName | NDUFA5 |
| identifier | Q16718 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Alternative splicing Electron transport Membrane Mitochondrion Mitochondrion inner membrane Proteomics identification Reference proteome Respiratory chain Transport |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | NDUFA5 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997847] ENSEMBL:ENSG00000128609 NDUFA5 [Homo sapiens] |
| secondaryIdentifier | NDUA5_HUMAN B2RD98 Q5H9R2 Q6IRX7 |
| sequenceLength | 116 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8970635] UniProt:Q16718-1 NDUFA5 [Homo sapiens] [ReferenceIsoform:8970636] UniProt:Q16718-2 NDUFA5 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:60599] NDUFA5 [mitochondrial inner membrane] [Homo sapiens] [EntityWithAccessionedSequence:9714749] NDUFA5 [endoplasmic reticulum membrane] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q16718 NDUFA5 (60600)
