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Details on Person UniProt:O43920 NDUFS5

Class:IdReferenceGeneProduct:60227
_chainChangeLoginitiator methionine:1 added on Fri February 6 2015;chain:2-106 added on Fri February 6 2015
_displayNameUniProt:O43920 NDUFS5
_timestamp2024-11-03 19:42:09
chainchain:1-106
checksum3D55402837DD99EE
commentFUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.SUBUNIT Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.INTERACTION Contains two C-X9-C motifs that are predicted to form a helix-coil-helix structure, permitting the formation of intramolecular disulfide bonds.SIMILARITY Belongs to the complex I NDUFS5 subunit family.
descriptionrecommendedName: NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 alternativeName: Complex I-15 kDa shortName: CI-15 kDa alternativeName: NADH-ubiquinone oxidoreductase 15 kDa subunit
geneNameNDUFS5
identifierO43920
isSequenceChangedFALSE
keyword3D-structure
Disulfide bond
Electron transport
Membrane
Mitochondrion
Mitochondrion inner membrane
Proteomics identification
Reference proteome
Respiratory chain
Transport
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameNDUFS5
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8999023] ENSEMBL:ENSG00000168653 NDUFS5 [Homo sapiens]
secondaryIdentifierNDUS5_HUMAN
sequenceLength106
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:60226] NDUFS5 [mitochondrial inner membrane] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:O43920 NDUFS5 (60227)