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Details on Person Diagram of Transport of vitamins, nucleosides, and related molecules, Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS), Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS), Defective SLC33A1 causes spastic paraplegia 42 (SPG42), Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M), Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS), Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C), and Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F)
| Class:Id | PathwayDiagram:601857 |
|---|---|
| _displayName | Diagram of Transport of vitamins, nucleosides, and related molecules, Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS), Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS), Defective SLC33A1 causes spastic paraplegia 42 (SPG42), Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M), Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS), Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C), and Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) |
| _timestamp | 2025-11-03 13:26:51 |
| created | [InstanceEdit:601858] D'Eustachio, P, 2010-04-15 |
| height | 1258 |
| modified | [InstanceEdit:1679954] Wu, G, 2011-10-20 [InstanceEdit:1937259] Rothfels, K, 2011-11-02 [InstanceEdit:3499327] Jassal, B, 2013-05-17 [InstanceEdit:3903040] Jassal, B, 2013-07-17 [InstanceEdit:3907273] Gillespie, ME, 2013-07-18 [InstanceEdit:4127408] Gillespie, ME, 2013-08-14 [InstanceEdit:5099910] Matthews, L, 2013-11-13 [InstanceEdit:5357422] Jassal, Bijay, 2014-03-21 [InstanceEdit:5359007] Jassal, Bijay, 2014-04-07 [InstanceEdit:5362168] Jassal, Bijay, 2014-04-15 [InstanceEdit:5627920] Jassal, Bijay, 2014-10-23 [InstanceEdit:5632829] Jassal, Bijay, 2014-10-29 [InstanceEdit:5649739] Jassal, Bijay, 2014-11-21 [InstanceEdit:5652118] Jassal, Bijay, 2014-11-27 [InstanceEdit:5653590] Jassal, Bijay, 2014-12-01 [InstanceEdit:5653623] Jassal, Bijay, 2014-12-01 [InstanceEdit:6789877] Jassal, Bijay, 2015-08-05 [InstanceEdit:6792750] Jassal, Bijay, 2015-08-27 [InstanceEdit:9632032] Jassal, Bijay, 2018-12-13 [InstanceEdit:9632475] D'Eustachio, Peter, 2018-12-18 [InstanceEdit:9632754] Jassal, Bijay, 2018-12-21 [InstanceEdit:9661801] Jassal, Bijay, 2019-09-18 [InstanceEdit:9697722] Jassal, Bijay, 2020-08-20 [InstanceEdit:9751090] Jassal, Bijay, 2021-08-18 [InstanceEdit:9751175] Matthews, Lisa, 2021-08-18 [InstanceEdit:9758372] Matthews, Lisa, 2021-11-11 [InstanceEdit:9758373] Matthews, Lisa, 2021-11-11 [InstanceEdit:9792611] D'Eustachio, Peter, 2022-05-27 [InstanceEdit:9916043] D'Eustachio, Peter, 2024-07-19 [InstanceEdit:9942373] Stephan, Ralf, 2025-03-15 [InstanceEdit:9955297] Stephan, Ralf, 2025-06-10 [InstanceEdit:9970834] D'Eustachio, Peter, 2025-11-03 |
| representedPathway | [Pathway:425397] Transport of vitamins, nucleosides, and related molecules [Homo sapiens] [Pathway:5619108] Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS) [Homo sapiens] [Pathway:5619063] Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS) [Homo sapiens] [Pathway:5619061] Defective SLC33A1 causes spastic paraplegia 42 (SPG42) [Homo sapiens] [Pathway:5619072] Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M) [Homo sapiens] [Pathway:5619083] Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS) [Homo sapiens] [Pathway:5619078] Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C) [Homo sapiens] [Pathway:5619037] Defective transport by SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) [Homo sapiens] |
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<displayName>ARL2:GTP</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="295" reactomeId="5250221" position="338 1158" bounds="281 1147 115 22" textPosition="281 1147" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableComplex id="319" reactomeId="5250201" position="513 1203" bounds="456 1192 115 22" textPosition="456 1192" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ARL2:GTP:ARL2BP</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="321" reactomeId="49741" position="491 1147" bounds="461 1136 61 22" textPosition="471 1136"> <Properties> <displayName>AAC1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="322" reactomeId="5250205" position="693 1210" bounds="634 1192 119 36" textPosition="634 1192" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ARL2:GTP:ARL2BP:SLC25A4</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="329" reactomeId="29370" position="490 1071" bounds="470 1056 41 30" textPosition="474 1060" /> <org.gk.render.RenderableChemical id="330" reactomeId="113593" position="598 1167" bounds="578 1152 40 30" textPosition="582 1156"> <Properties> <displayName>ATP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="331" reactomeId="113592" position="575 1065" bounds="555 1050 40 30" textPosition="559 1054" /> <org.gk.render.RenderableChemical id="332" reactomeId="113581" position="762 1176" bounds="742 1161 41 30" textPosition="746 1165"> <Properties> <displayName>ADP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="334" reactomeId="29370" position="1030 1142" bounds="1010 1127 41 30" textPosition="1014 1131" /> <org.gk.render.RenderableChemical id="335" reactomeId="113593" position="917 1190" bounds="897 1175 40 30" textPosition="901 1179" /> <org.gk.render.RenderableEntitySet id="338" reactomeId="187453" position="833 1213" bounds="775 1202 117 22" textPosition="775 1202"> <Properties> <displayName>SLC25A5,6 dimers</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="345" reactomeId="162756" position="593 911" bounds="549 896 89 30" textPosition="553 900"> <Properties> <displayName>UDP-GlcNAc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="347" reactomeId="914003" position="765 918" bounds="721 903 89 30" textPosition="725 907" /> <org.gk.render.RenderableChemical id="351" reactomeId="29410" position="607 1017" bounds="561 1001 92 32" textPosition="578 1006" /> <org.gk.render.RenderableChemical id="352" reactomeId="744227" position="750 1021" bounds="706 1004 88 35" textPosition="721 1010"> <Properties> <displayName>UDP-Glc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="354" reactomeId="1889970" position="784 844" bounds="747 829 74 31" textPosition="751 833" /> <org.gk.render.RenderableChemical id="356" reactomeId="735698" position="754 793" bounds="733 778 42 30" textPosition="737 782" /> <org.gk.render.RenderableChemical id="358" reactomeId="109402" position="613 792" bounds="592 777 42 30" textPosition="596 781" /> <org.gk.render.RenderableChemical id="359" reactomeId="742343" position="1344 751" bounds="1325 736 39 31" textPosition="1329 740" /> <org.gk.render.RenderableChemical id="360" reactomeId="158466" position="1217 755" bounds="1198 740 39 31" textPosition="1202 744"> <Properties> <displayName>PAP</displayName> </Properties> </org.gk.render.RenderableChemical> </Nodes> <Edges> <org.gk.render.RenderableReaction id="26" reactomeId="429581" points="157 474, 180 474, 204 475" position="180 474" lineWidth="1.0"> <Inputs> <Input id="2" points="119 447" /> <Input id="3" stoichiometry="2" points="108 493" /> </Inputs> <Outputs> <Output id="4" stoichiometry="2" points="255 497" /> <Output id="5" points="244 447" /> </Outputs> <Catalysts> <Catalyst id="219" points="180 513" /> </Catalysts> <Properties> <displayName>SLC5A6 transports vitamins from extracellular region to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27" reactomeId="109530" points="320 108, 319 133, 318 157" position="319 133" lineWidth="1.0"> <Inputs> <Input id="7" points="248 77" /> <Input id="10" points="334 91" /> </Inputs> <Outputs> <Output id="8" points="270 197" /> <Output id="11" points="341 171" /> </Outputs> <Catalysts> <Catalyst id="9" points="287 130" /> </Catalysts> <Properties> <displayName>Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="28" reactomeId="109538" points="421 105, 420 131, 421 152" position="420 131" lineWidth="1.0"> <Inputs> <Input id="12" points="461 61" /> <Input id="10" stoichiometry="2" points="371 82" /> </Inputs> <Outputs> <Output id="13" points="477 201" /> <Output id="11" stoichiometry="2" points="390 171" /> </Outputs> <Catalysts> <Catalyst id="14" points="460 131" /> </Catalysts> <Properties> <displayName>Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="29" reactomeId="109539" points="796 98, 794 129, 794 150" position="794 129" lineWidth="1.0"> <Inputs> <Input id="15" points="835 62" /> <Input id="19" points="749 81" /> </Inputs> <Outputs> <Output id="16" points="834 183" /> <Output id="18" points="749 170" /> </Outputs> <Catalysts> <Catalyst id="17" points="817 128" /> </Catalysts> <Properties> <displayName>Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="30" reactomeId="109534" points="502 201, 554 117, 489 61" position="554 117" lineWidth="1.0"> <Inputs> <Input id="13" /> </Inputs> <Outputs> <Output id="12" /> </Outputs> <Catalysts> <Catalyst id="213" points="591 121" /> </Catalysts> <Properties> <displayName>Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="31" reactomeId="109529" points="1052 179, 1051 122, 1041 82" position="1051 122" lineWidth="1.0"> <Inputs> <Input id="23" /> </Inputs> <Outputs> <Output id="24" /> </Outputs> <Catalysts> <Catalyst id="210" points="1020 124" /> </Catalysts> <Properties> <displayName>Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="32" reactomeId="109536" points="486 61, 556 137, 504 201" position="556 137" lineWidth="1.0"> <Inputs> <Input id="12" /> </Inputs> <Outputs> <Output id="13" /> </Outputs> <Catalysts> <Catalyst id="213" points="591 131" /> </Catalysts> <Properties> <displayName>Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="33" reactomeId="109527" points="1044 82, 1073 136, 1056 179" position="1073 136" lineWidth="1.0"> <Inputs> <Input id="24" /> </Inputs> <Outputs> <Output id="23" /> </Outputs> <Catalysts> <Catalyst id="210" points="1020 131" /> </Catalysts> <Properties> <displayName>Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="34" reactomeId="727749" points="446 356, 402 351, 361 356" position="402 351" lineWidth="1.0"> <Inputs> <Input id="35" /> </Inputs> <Outputs> <Output id="36" /> </Outputs> <Catalysts> <Catalyst id="37" points="405 399" /> </Catalysts> <Properties> <displayName>SLC29A3 transports nucleosides from lysosomal lumen to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="38" reactomeId="727767" points="361 366, 415 370, 446 367" position="415 370" lineWidth="1.0"> <Inputs> <Input id="36" /> </Inputs> <Outputs> <Output id="35" /> </Outputs> <Catalysts> <Catalyst id="37" points="408 399" /> </Catalysts> <Properties> <displayName>SLC29A3 transports nucleosides from cytosol to lysosomal lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="39" reactomeId="727768" points="216 269, 175 266, 137 269" position="175 266" lineWidth="1.0"> <Inputs> <Input id="40" /> </Inputs> <Outputs> <Output id="41" /> </Outputs> <Catalysts> <Catalyst id="42" points="179 317" /> </Catalysts> <Properties> <displayName>Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="43" reactomeId="727740" points="137 281, 187 288, 216 282" position="187 288" lineWidth="1.0"> <Inputs> <Input id="41" /> </Inputs> <Outputs> <Output id="40" /> </Outputs> <Catalysts> <Catalyst id="42" points="182 317" /> </Catalysts> <Properties> <displayName>Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="45" reactomeId="727759" points="809 381, 809 435, 809 477" position="809 435" lineWidth="1.0"> <Inputs> <Input id="46" /> </Inputs> <Outputs> <Output id="47" /> </Outputs> <Catalysts> <Catalyst id="48" points="754 436" /> </Catalysts> <Properties> <displayName>SLC33A1 transports Ac-CoA from cytosol to Golgi lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="84" reactomeId="741449" points="1310 717, 1287 717, 1244 717" position="1287 717" lineWidth="1.0"> <Inputs> <Input id="55" points="1333 717" /> <Input id="359" points="1328 733" /> </Inputs> <Outputs> <Output id="360" points="1228 737" /> <Output id="65" points="1201 719" /> </Outputs> <Catalysts> <Catalyst id="198" points="1284 690" /> </Catalysts> <Properties> <displayName>SLC35B2,3 exchange cytosolic PAPS with Golgi PAP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="85" reactomeId="742354" points="645 677, 680 682, 773 656" position="680 682" lineWidth="1.0"> <Inputs> <Input id="207" /> </Inputs> <Outputs> <Output id="182" /> </Outputs> <Catalysts> <Catalyst id="157" points="676 662" /> </Catalysts> <Properties> <displayName>SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="86" reactomeId="744230" points="1281 891, 1280 981, 1272 944" position="1280 981" lineWidth="1.0"> <Inputs> <Input id="64" points="1338 880" /> <Input id="62" points="1228 893" /> </Inputs> <Outputs> <Output id="59" points="1335 937" /> <Output id="71" points="1249 940" /> </Outputs> <Catalysts> <Catalyst id="51" points="713 877" /> </Catalysts> <Properties> <displayName>SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="87" reactomeId="727807" points="1024 438, 996 435, 995 436" position="996 435" lineWidth="1.0"> <Inputs> <Input id="214" points="1071 394" /> <Input id="58" points="1052 457" /> </Inputs> <Outputs> <Output id="60" points="994 369" /> <Output id="70" points="994 486" /> </Outputs> <Catalysts> <Catalyst id="75" points="948 433" /> </Catalysts> <Properties> <displayName>SLC35A1 exchanges CMP-Neu5Ac for CMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="88" reactomeId="174368" points="357 845, 357 844, 357 846" position="357 844" lineWidth="1.0"> <Inputs> <Input id="50" points="406 813" /> <Input id="209" points="317 812" /> </Inputs> <Outputs> <Output id="72" points="323 883" /> <Output id="201" points="398 879" /> </Outputs> <Catalysts> <Catalyst id="57" points="301 844" /> </Catalysts> <Properties> <displayName>SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="89" reactomeId="741450" points="678 593, 680 593, 637 577" position="680 593" lineWidth="1.0"> <Inputs> <Input id="102" points="808 576" /> <Input id="205" points="626 602" /> </Inputs> <Outputs> <Output id="73" points="592 558" /> <Output id="182" points="779 626" /> </Outputs> <Catalysts> <Catalyst id="54" points="678 550" /> </Catalysts> <Properties> <displayName>SLC35A3 exchanges UDP-GlcNAc for UMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="90" reactomeId="744231" points="684 925, 678 916, 684 927" position="678 916" lineWidth="1.0"> <Inputs> <Input id="80" points="733 956" /> <Input id="345" points="641 917" /> </Inputs> <Outputs> <Output id="103" points="623 957" /> <Output id="347" points="718 922" /> </Outputs> <Catalysts> <Catalyst id="51" points="678 886" /> </Catalysts> <Properties> <displayName>SLC35D2 exchanges UDP-GlcNAc for UMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="91" reactomeId="742373" points="639 717, 679 719, 730 719" position="679 719" lineWidth="1.0"> <Inputs> <Input id="69" /> </Inputs> <Outputs> <Output id="79" /> </Outputs> <Catalysts> <Catalyst id="78" points="677 739" /> </Catalysts> <Properties> <displayName>SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="92" reactomeId="735702" points="1186 435, 1186 435, 1186 435" position="1186 435" lineWidth="1.0"> <Inputs> <Input id="76" points="1185 334" /> <Input id="100" points="1213 472" /> </Inputs> <Outputs> <Output id="63" points="1184 515" /> <Output id="105" points="1220 371" /> </Outputs> <Catalysts> <Catalyst id="52" points="1223 432" /> </Catalysts> <Properties> <displayName>SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="93" reactomeId="742345" points="1314 826, 1281 825, 1257 826" position="1281 825" lineWidth="1.0"> <Inputs> <Input id="62" points="1228 880" /> <Input id="68" points="1329 826" /> </Inputs> <Outputs> <Output id="59" points="1344 917" /> <Output id="66" points="1218 828" /> </Outputs> <Catalysts> <Catalyst id="53" points="1282 796" /> </Catalysts> <Properties> <displayName>SLC35C1 transport GDP-Fuc from cytosol to Golgi lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="158" reactomeId="879585" points="130 669, 181 669, 248 669" position="181 669" lineWidth="1.0"> <Inputs> <Input id="159" /> </Inputs> <Outputs> <Output id="160" /> </Outputs> <Catalysts> <Catalyst id="161" points="180 639" /> </Catalysts> <Properties> <displayName>SLC27A1,4,6 transport LCFAs from extracellular region to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="215" reactomeId="5229283" points="77 790, 78 789, 78 823" position="78 789" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="216" points="47 763" /> <Input id="217" points="106 766" /> </Inputs> <Outputs> <Output id="218" /> </Outputs> <Properties> <displayName>LCNs bind lipids</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="292" reactomeId="5250217" points="255 1156, 254 1156, 278 1156" position="254 1156" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="293" points="234 1143" /> <Input id="294" points="239 1178" /> </Inputs> <Outputs> <Output id="295" /> </Outputs> <Properties> <displayName>ARL2:GTP binds ARL2BP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="318" reactomeId="5250210" points="399 1158, 433 1158, 493 1189" position="433 1158" lineWidth="1.0"> <Inputs> <Input id="295" /> </Inputs> <Outputs> <Output id="319" /> </Outputs> <Properties> <displayName>ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="320" reactomeId="5250209" points="559 1180, 559 1180, 631 1196" position="559 1180" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="319" points="535 1189" /> <Input id="321" points="513 1161" /> </Inputs> <Outputs> <Output id="322" /> </Outputs> <Properties> <displayName>ARL2:GTP:ARL2BP binds SLC25A4</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="328" reactomeId="5672027" points="644 1138, 689 1138, 729 1137" position="689 1138" lineWidth="1.0"> <Inputs> <Input id="329" points="514 1079" /> <Input id="330" points="621 1154" /> </Inputs> <Outputs> <Output id="331" points="598 1074" /> <Output id="332" points="749 1158" /> </Outputs> <Catalysts> <Catalyst id="322" points="692 1189" /> </Catalysts> <Properties> <displayName>ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="333" reactomeId="163215" points="947 1138, 832 1138, 792 1139" position="832 1138" lineWidth="1.0"> <Inputs> <Input id="334" points="1007 1141" /> <Input id="335" points="925 1172" /> </Inputs> <Outputs> <Output id="332" points="774 1158" /> <Output id="331" points="598 1071" /> </Outputs> <Catalysts> <Catalyst id="338" points="832 1196" /> </Catalysts> <Properties> <displayName>SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="350" reactomeId="9792608" points="672 980, 674 967, 672 977" position="674 967" lineWidth="1.0"> <Inputs> <Input id="351" points="635 998" /> <Input id="80" points="733 971" /> </Inputs> <Outputs> <Output id="352" points="718 1001" /> <Output id="103" points="623 969" /> </Outputs> <Catalysts> <Catalyst id="51" points="675 886, 650 962" /> </Catalysts> <Properties> <displayName>SLC35D2 exchanges UDP-D-glucose for UMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="353" reactomeId="9912889" points="668 831, 677 828, 691 828" position="677 828" lineWidth="1.0"> <Inputs> <Input id="50" points="467 800" /> <Input id="356" points="730 802" /> </Inputs> <Outputs> <Output id="354" points="744 837" /> <Output id="358" points="637 801" /> </Outputs> <Catalysts> <Catalyst id="51" points="678 858" /> </Catalysts> <Properties> <displayName>SLC35D2 exchanges UDP-GlcA for UMP</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process> |
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No pathways have been reviewed or authored by Diagram of Transport of vitamins, nucleosides, and related molecules, Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS), Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS), Defective SLC33A1 causes spastic paraplegia 42 (SPG42), Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M), Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS), Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C), and Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) (601857)
