THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE.
WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE
Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q02505 MUC3A
Class:Id
ReferenceGeneProduct:59705
_chainChangeLog
signal peptide:1-21 added on Sat February 7 2015;chain:22-2541 added on Sat February 7 2015;signal peptide:1-21 removed on Fri May 6 2016;chain:22-2541 removed on Fri May 6 2016;signal peptide:1-15 added on Fri May 6 2016;chain:16-3323 added on Fri May 6 2016
_displayName
UniProt:Q02505 MUC3A
_timestamp
2024-11-03 19:42:02
chain
signal peptide:1-15 chain:16-3323
checksum
8C6E21ADD26637EF
comment
FUNCTION Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling.SUBCELLULAR LOCATION Additional isoforms seem to exist.TISSUE SPECIFICITY Broad specificity; small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas and gall bladder.PTM Highly O-glycosylated and probably also N-glycosylated.MISCELLANEOUS May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.SEQUENCE CAUTION This sequence is incomplete at 5' and 3' ends and extensively differs from that shown.SEQUENCE CAUTION This sequence is incomplete at 5' and 3' ends and extensively differs from that shown.
