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Details on Person UniProt:P25713 MT3
| Class:Id | ReferenceGeneProduct:59633 |
|---|---|
| _chainChangeLog | chain:1-68 added on Fri February 6 2015 |
| _displayName | UniProt:P25713 MT3 |
| _timestamp | 2024-11-03 19:37:37 |
| chain | chain:1-68 |
| checksum | 59801ECF5BC8A406 |
| comment | FUNCTION Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.INTERACTION Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain.SIMILARITY Belongs to the metallothionein superfamily. Type 1 family. |
| description | recommendedName: Metallothionein-3 shortName: MT-3 alternativeName: GIFB shortName: GIF alternativeName: Growth inhibitory factor alternativeName: Metallothionein-III shortName: MT-III |
| geneName | MT3 |
| identifier | P25713 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Copper Direct protein sequencing Metal-binding Metal-thiolate cluster Phosphoprotein Proteomics identification Reference proteome Zinc |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | MT3 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:5661303] ENSEMBL:ENSG00000087250 MT3 [Homo sapiens] |
| secondaryIdentifier | MT3_HUMAN Q2V574 |
| sequenceLength | 68 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5660396] MT3 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P25713 MT3 (59633)
