Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:P13640 MT1G
| Class:Id | ReferenceGeneProduct:59619 |
|---|---|
| _chainChangeLog | chain:1-62 added on Fri February 6 2015 |
| _displayName | UniProt:P13640 MT1G |
| _timestamp | 2024-11-03 19:52:40 |
| chain | chain:1-62 |
| checksum | A1B390F5899DD040 |
| comment | FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.SUBUNIT Monomer.INTERACTION Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.SIMILARITY Belongs to the metallothionein superfamily. Type 1 family. |
| description | recommendedName: Metallothionein-1G shortName: MT-1G alternativeName: Metallothionein-1K shortName: MT-1K alternativeName: Metallothionein-IG shortName: MT-IG |
| geneName | MT1G MT1K MT1M |
| identifier | P13640 |
| isSequenceChanged | FALSE |
| keyword | Acetylation Alternative splicing Cadmium Copper Direct protein sequencing Metal-binding Metal-thiolate cluster Phosphoprotein Proteomics identification Reference proteome Zinc |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | MT1G |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:5660097] ENSEMBL:ENSG00000125144 MT1G [Homo sapiens] |
| secondaryIdentifier | MT1G_HUMAN P80296 |
| sequenceLength | 62 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:238019] UniProt:P13640-2 MT1G [Homo sapiens] [ReferenceIsoform:402927] UniProt:P13640-1 MT1G [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:5660415] MT1G [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:8958114] MT1G [extracellular region] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P13640 MT1G (59619)
