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Details on Person UniProt:P07438 MT1B
| Class:Id | ReferenceGeneProduct:59613 |
|---|---|
| _chainChangeLog | chain:1-61 added on Sat February 7 2015 |
| _displayName | UniProt:P07438 MT1B |
| _timestamp | 2024-11-03 19:41:58 |
| chain | chain:1-61 |
| checksum | 8DC566E5462810D3 |
| comment | FUNCTION Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.SUBUNIT Monomer.INTERACTION Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.SIMILARITY Belongs to the metallothionein superfamily. Type 1 family. |
| description | recommendedName: Metallothionein-1B shortName: MT-1B alternativeName: Metallothionein-IB shortName: MT-IB |
| geneName | MT1B MT1Q |
| identifier | P07438 |
| isSequenceChanged | FALSE |
| keyword | Cadmium Copper Metal-binding Metal-thiolate cluster Proteomics identification Reference proteome Zinc |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | MT1B |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:5660065] ENSEMBL:ENSG00000169688 MT1B [Homo sapiens] |
| secondaryIdentifier | MT1B_HUMAN Q86YX0 |
| sequenceLength | 61 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5660371] MT1B [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P07438 MT1B (59613)
