Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person MAP2K1 [cytosol]

Class:IdEntityWithAccessionedSequence:59502
_displayNameMAP2K1 [cytosol]
_timestamp2025-02-18 19:21:37
compartment[Compartment:70101] cytosol
endCoordinate393
modified[InstanceEdit:109781] Schmidt, EE, 2004-01-21 04:32:59
[InstanceEdit:112335] Schmidt, EE, 2004-04-27 10:09:34
[InstanceEdit:112397] Schmidt, EE, 2004-04-29 09:21:20
[InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08
[InstanceEdit:3132750] Wu, G, 2013-02-13
[InstanceEdit:3322333] Wu, G, 2013-05-03
[InstanceEdit:3322334] Wu, G, 2013-05-03
[InstanceEdit:9938686] D'Eustachio, Peter, 2025-02-18
nameMAP2K1
MEK1
Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1)
Dual specificity mitogen-activated protein kinase kinase 1
MAP kinase kinase 1
MAPKK 1
ERK activator kinase 1
MAPK/ERK kinase 1
referenceEntity[ReferenceGeneProduct:59503] UniProt:Q02750 MAP2K1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:369381] R-HSA-59502.2
startCoordinate1
(hasComponent)[Complex:109794] Activated RAF1 complex:MEK1 [plasma membrane] [Homo sapiens]
[Complex:5672683] MAP2K1 dimer [cytosol] [Homo sapiens]
[Complex:5672686] MAP2K1:MAPK2K2 heterodimer [cytosol] [Homo sapiens]
(hasMember)[DefinedSet:112336] MAP2K1 [cytosol] [Homo sapiens]
[DefinedSet:112398] MEK [cytosol] [Homo sapiens]
[DefinedSet:451647] MAP2K1,MAP2K4 [cytosol] [Homo sapiens]
[DefinedSet:9682898] CDK2,GSK3,CSNK2,MAP2K [cytosol] [Homo sapiens]
(input)[Reaction:5211340] Anthrax lef cleaves target cell MAP2K1 (MEK1) [Homo sapiens]
(updatedInstance)[_UpdateTracker:9878943] Update Tracker - [EntityWithAccessionedSequence:59502] MAP2K1 [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate]
[_UpdateTracker:9882604] Update Tracker - [EntityWithAccessionedSequence:59502] MAP2K1 [cytosol] - v45:[addName]
[_UpdateTracker:9939851] Update Tracker - [EntityWithAccessionedSequence:59502] MAP2K1 [cytosol] - v92:[modifyStartCoordinate]
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No pathways have been reviewed or authored by MAP2K1 [cytosol] (59502)