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Details on Person UniProt:P49286 MTNR1B
| Class:Id | ReferenceGeneProduct:59327 |
|---|---|
| _chainChangeLog | chain:1-362 added on Sat February 7 2015 |
| _displayName | UniProt:P49286 MTNR1B |
| _timestamp | 2023-11-03 18:02:38 |
| chain | chain:1-362 |
| checksum | EECD78649DD79121 |
| comment | FUNCTION High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.SUBUNIT Interacts with GPR61, GPR62 and GPR135 (PubMed:28827538).INTERACTION Expressed in retina and less in brain and hippocampus.SIMILARITY Belongs to the G-protein coupled receptor 1 family.ONLINE INFORMATION Melatonin receptor entry |
| description | recommendedName: Melatonin receptor type 1B shortName: Mel-1B-R shortName: Mel1b receptor |
| geneName | MTNR1B |
| identifier | P49286 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | MTNR1B |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8999626] ENSEMBL:ENSG00000134640 MTNR1B [Homo sapiens] |
| secondaryIdentifier | MTR1B_HUMAN |
| sequenceLength | 362 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:419349] MTNR1B [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P49286 MTNR1B (59327)
