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Details on Person UniProt:P14209 CD99
| Class:Id | ReferenceGeneProduct:59253 |
|---|---|
| _chainChangeLog | signal peptide:1-22 added on Fri February 6 2015;chain:23-185 added on Fri February 6 2015 |
| _displayName | UniProt:P14209 CD99 |
| _timestamp | 2024-11-03 20:09:14 |
| chain | signal peptide:1-22 chain:23-185 |
| checksum | C302E09E6B022EAB |
| comment | FUNCTION Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity).SUBCELLULAR LOCATION Extensively O-glycosylated.MISCELLANEOUS The gene coding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.SIMILARITY Belongs to the CD99 family. |
| description | recommendedName: CD99 antigen alternativeName: 12E7 alternativeName: E2 antigen alternativeName: Protein MIC2 alternativeName: T-cell surface glycoprotein E2 cdAntigenNameCD99/cdAntigenName |
| geneName | CD99 MIC2 MIC2X MIC2Y |
| identifier | P14209 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Cell adhesion Direct protein sequencing Glycoprotein Membrane Phosphoprotein Proteomics identification Reference proteome Signal Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | CD99 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8991170] ENSEMBL:ENSG00000002586 CD99 [Homo sapiens] |
| secondaryIdentifier | CD99_HUMAN A6NIW1 O00518 Q6ICV7 |
| sequenceLength | 185 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:150304] UniProt:P14209-2 CD99 [Homo sapiens] [ReferenceIsoform:402947] UniProt:P14209-1 CD99 [Homo sapiens] [ReferenceIsoform:8975480] UniProt:P14209-3 CD99 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:8862085] CD99 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8862093] CD99 [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:P14209 CD99 (59253)
