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Details on Person UniProt:Q13084 MRPL28
| Class:Id | ReferenceGeneProduct:58915 |
|---|---|
| _chainChangeLog | transit peptide:1-55 added on Sat February 7 2015;chain:56-256 added on Sat February 7 2015 |
| _displayName | UniProt:Q13084 MRPL28 |
| _timestamp | 2024-11-03 20:07:24 |
| chain | transit peptide:1-55 chain:56-256 |
| checksum | 6578FD1E98FC5A6E |
| comment | SUBUNIT Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:11551941, PubMed:25278503, PubMed:28892042, PubMed:35177605). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins (PubMed:11551941, PubMed:25278503). Interacts with OXA1L.INTERACTION Found in a variety of normal tissues including spleen, testes, thymus, liver, kidney, brain, adrenal, lung and retinal tissue.MISCELLANEOUS Potentially represents an important therapeutic reagent for HLA-A24 patients. This antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290 in the context of HLA-A24.SIMILARITY Belongs to the bacterial ribosomal protein bL28 family. |
| description | recommendedName: fullName evidence="10"Large ribosomal subunit protein bL28m alternativeName: 39S ribosomal protein L28, mitochondrial shortName: L28mt shortName: MRP-L28 alternativeName: Melanoma antigen p15 alternativeName: Melanoma-associated antigen recognized by T-lymphocytes |
| geneName | MRPL28 MAAT1 |
| identifier | Q13084 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Mitochondrion Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein Transit peptide |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | MRPL28 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9002020] ENSEMBL:ENSG00000086504 MRPL28 [Homo sapiens] |
| secondaryIdentifier | RM28_HUMAN B2RCM4 D3DU46 Q4TT39 Q96S26 Q9BQD8 Q9BR04 |
| sequenceLength | 256 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5368246] MRPL28 [mitochondrial inner membrane] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q13084 MRPL28 (58915)
