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Details on Person UniProt:P01229 LHB
| Class:Id | ReferenceGeneProduct:58715 |
|---|---|
| _chainChangeLog | signal peptide:1-20 added on Sat February 7 2015;chain:21-141 added on Sat February 7 2015 |
| _displayName | UniProt:P01229 LHB |
| _timestamp | 2025-02-21 18:48:27 |
| chain | signal peptide:1-20 chain:21-141 |
| checksum | E411766253113F7C |
| comment | FUNCTION Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.SUBUNIT Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.INTERACTION Pituitary gland.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the glycoprotein hormones subunit beta family.ONLINE INFORMATION Luteinizing hormone entry |
| description | recommendedName: Lutropin subunit beta shortName: Lutropin beta chain alternativeName: Luteinizing hormone subunit beta shortName: LH-B shortName: LSH-B shortName: LSH-beta |
| geneName | LHB |
| identifier | P01229 |
| isSequenceChanged | FALSE |
| keyword | Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hormone Hypogonadotropic hypogonadism Proteomics identification Reference proteome Secreted Signal |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | LHB |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9002442] ENSEMBL:ENSG00000104826 LHB [Homo sapiens] |
| secondaryIdentifier | LSHB_HUMAN Q9UDI0 |
| sequenceLength | 141 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:378982] LHB [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:6786345] S-glyco-LHB [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:6793929] S-glyco-LHB [Golgi lumen] [Homo sapiens] [EntityWithAccessionedSequence:6793932] LHB [Golgi lumen] [Homo sapiens] |
| (referenceSequence) | [GroupModifiedResidue:6786332] glycosylated residue (4-O-sulfo-N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl group) at 50 [GroupModifiedResidue:6786390] glycosylated residue (N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl group) at 50 |
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No pathways have been reviewed or authored by UniProt:P01229 LHB (58715)
