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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:P23490 LORICRIN

Class:IdReferenceGeneProduct:58671
_chainChangeLogchain:1-312 added on Sat February 7 2015
_displayNameUniProt:P23490 LORICRIN
_timestamp2024-11-03 19:37:21
chainchain:1-312
checksumA64248C3E4FD698E
commentFUNCTION Major keratinocyte cell envelope protein.SUBCELLULAR LOCATION Substrate of transglutaminases. Some glutamines and lysines are cross-linked to other loricrin molecules and to SPRRs proteins.PTM Contains inter- or intramolecular disulfide-bonds.DISEASE The disease is caused by variants affecting the gene represented in this entry.
descriptionrecommendedName: fullName evidence="9"Loricrin
geneNameLORICRIN
LOR
LRN
identifierP23490
isSequenceChangedFALSE
keywordCytoplasm
Direct protein sequencing
Disulfide bond
Ichthyosis
Isopeptide bond
Keratinization
Nucleus
Palmoplantar keratoderma
Proteomics identification
Reference proteome
Repeat
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameLORICRIN
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8999600] ENSEMBL:ENSG00000203782 LORICRIN [Homo sapiens]
secondaryIdentifierLORI_HUMAN
Q5T869
Q5XKF8
sequenceLength312
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:6810848] LORICRIN [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:8847711] LORICRIN [cornified envelope] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:P23490 LORICRIN (58671)