Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person PRKCA [cytosol]
Class:Id EntityWithAccessionedSequence:58196
_displayName PRKCA [cytosol]
_timestamp 2017-11-19 05:19:03
compartment [Compartment:70101] cytosol
endCoordinate 672
literatureReference [LiteratureReference:9029469] Resting distribution and stimulated translocation of protein kinase C isoforms alpha, epsilon and zeta in response to bradykinin and TNF in human endothelial cells
modified [InstanceEdit:111852] Schmidt, EE, 2004-03-24 06:49:11 [InstanceEdit:112036] Schmidt, EE, 2004-04-06 11:04:06 [InstanceEdit:112269] Schmidt, EE, 2004-04-16 12:22:36 [InstanceEdit:113474] Schmidt, EE, 2004-05-20 07:56:43 [InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08 [InstanceEdit:114498] de Bono, B, 2004-08-04 09:17:50 [InstanceEdit:426264] Jupe, S, 2009-06-15 [InstanceEdit:3632907] Wu, G, 2013-05-28 [InstanceEdit:9029474] May, Bruce, 2017-11-19
name PRKCA Protein kinase C, alpha type PKC-alpha PKC-A
referenceEntity [ReferenceGeneProduct:58197] UniProt:P17252 PRKCA [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:362793] R-HSA-58196.2
startCoordinate 2
(activeUnit) [CatalystActivity:400010] protein serine/threonine kinase activity of Protein Kinase C, alpha type: DAG [plasma membrane]
(hasCandidate) [CandidateSet:9839179] Keratinocyte PKCs [cytosol] [Homo sapiens]
(hasComponent) [Complex:418838] pUnc5a:PICK1:PKCalpha [plasma membrane] [Homo sapiens] [Complex:422275] Protein Kinase C, alpha type: DAG [plasma membrane] [Homo sapiens] [Complex:1433473] p-KIT (S741,746):PKC alpha [plasma membrane] [Homo sapiens]
(hasMember) [DefinedSet:111853] Protein kinase C [cytosol] [Homo sapiens] [DefinedSet:111999] Protein kinase C, conventional isoforms (alpha, beta-1, beta-2, gamma) [cytosol] [Homo sapiens] [DefinedSet:112001] Protein kinase C (alpha, gamma, delta) [cytosol] [Homo sapiens] [DefinedSet:113483] Protein kinase C (alpha, beta, gamma, zeta) [cytosol] [Homo sapiens] [DefinedSet:114528] Protein Kinase C, conventional [cytosol] [Homo sapiens] [DefinedSet:5218761] PKCA,PKCB,PKCD,PKCZ [cytosol] [Homo sapiens] [DefinedSet:8855913] RET interactors [cytosol] [Homo sapiens]
(input) [Reaction:400015] Diacylgycerol activates Protein kinase C, alpha type [Homo sapiens] [Reaction:418864] Phosphorylation of Unc5a by PKCalpha-'step to endocytosis' [Homo sapiens] [Reaction:1433508] PKC alpha interacts with and phosphorylates KIT [Homo sapiens]
(physicalEntity) [CatalystActivity:418860] calcium,diacylglycerol-dependent serine/threonine kinase activity of PRKCA [cytosol] [CatalystActivity:9860667] diacylglycerol binding activity of PRKCA [cytosol]
(updatedInstance) [_UpdateTracker:9868305] Update Tracker - [EntityWithAccessionedSequence:58196] PRKCA [cytosol] - v30:[modifyEndCoordinate, modifyStartCoordinate] [_UpdateTracker:9887248] Update Tracker - [EntityWithAccessionedSequence:58196] PRKCA [cytosol] - v45:[addName] [_UpdateTracker:9898914] Update Tracker - [EntityWithAccessionedSequence:58196] PRKCA [cytosol] - v64:[addLiteratureReference]
[Change default viewing format]
List...
Pathways
No pathways have been reviewed or authored by PRKCA [cytosol] (58196)