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Details on Person UniProt:P13646 KRT13
| Class:Id | ReferenceGeneProduct:57701 |
|---|---|
| _chainChangeLog | chain:1-458 added on Fri February 6 2015 |
| _displayName | UniProt:P13646 KRT13 |
| _timestamp | 2024-11-03 20:19:38 |
| chain | chain:1-458 |
| checksum | A51AECFD6195ACB4 |
| comment | FUNCTION Type 1 keratin (Probable). Maintains postnatal tongue mucosal cell homeostasis and tissue organization in response to mechanical stress, potentially via regulation of the G1/S phase cyclins CCNE1 and CCNE2 (By similarity).SUBUNIT Heterotetramer of two type I and two type II keratins.INTERACTION Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.PTM O-glycosylated; glycans consist of single N-acetylglucosamine residues.DISEASE The disease is caused by variants affecting the gene represented in this entry.MISCELLANEOUS There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).SIMILARITY Belongs to the intermediate filament family.ONLINE INFORMATION Keratin-13 entry |
| description | recommendedName: Keratin, type I cytoskeletal 13 alternativeName: Cytokeratin-13 shortName: CK-13 alternativeName: Keratin-13 shortName: K13 |
| geneName | KRT13 |
| identifier | P13646 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Coiled coil Direct protein sequencing Disease variant Glycoprotein Intermediate filament Keratin Methylation Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | KRT13 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9001223] ENSEMBL:ENSG00000171401 KRT13 [Homo sapiens] |
| secondaryIdentifier | K1C13_HUMAN Q53G54 Q6AZK5 Q8N240 |
| sequenceLength | 458 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:233856] UniProt:P13646-2 KRT13 [Homo sapiens] [ReferenceIsoform:402928] UniProt:P13646-1 KRT13 [Homo sapiens] [ReferenceIsoform:8976060] UniProt:P13646-3 KRT13 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:6809591] KRT13 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P13646 KRT13 (57701)
