Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person UniProt:O75578 ITGA10

Class:IdReferenceGeneProduct:57585
_chainChangeLogsignal peptide:1-22 added on Fri February 6 2015;chain:23-1167 added on Fri February 6 2015
_displayNameUniProt:O75578 ITGA10
_timestamp2024-08-09 18:52:43
chainsignal peptide:1-22
chain:23-1167
checksum2F7FF938B4C0CBAC
commentFUNCTION Integrin alpha-10/beta-1 is a receptor for collagen.SUBUNIT Heterodimer of an alpha and a beta subunit. Alpha-10 associates with beta-1.SUBCELLULAR LOCATION Widely expressed with highest expression in muscle and heart. Found in articular cartilage.DOMAIN The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.SIMILARITY Belongs to the integrin alpha chain family.
descriptionrecommendedName: Integrin alpha-10
geneNameITGA10
UNQ468/PRO827
identifierO75578
isSequenceChangedFALSE
keywordAlternative splicing
Calcium
Cell adhesion
Disulfide bond
Glycoprotein
Integrin
Magnesium
Membrane
Metal-binding
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane
Transmembrane helix
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
nameITGA10
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8997763] ENSEMBL:ENSG00000143127 ITGA10 [Homo sapiens]
secondaryIdentifierITA10_HUMAN
B2RAM4
B2RTV5
Q6UXJ6
Q9UHZ8
sequenceLength1167
species[Species:48887] Homo sapiens
(isoformParent)[ReferenceIsoform:233119] UniProt:O75578-2 ITGA10 [Homo sapiens]
[ReferenceIsoform:401870] UniProt:O75578-1 ITGA10 [Homo sapiens]
[ReferenceIsoform:8977458] UniProt:O75578-3 ITGA10 [Homo sapiens]
(referenceEntity)[EntityWithAccessionedSequence:215933] ITGA10 [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:O75578 ITGA10 (57585)