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Details on Person Ttf-I:rRNA Promoter:Ercc6:Ehmt2 complex dimethylates histone H3 at lysine-9

Class:Id	Reaction:573373
_displayName	Ttf-I:rRNA Promoter:Ercc6:Ehmt2 complex dimethylates histone H3 at lysine-9
_doRelease	TRUE
_timestamp	2016-08-16 15:20:37
authored	[InstanceEdit:565730] May, B, 2010-04-06
catalystActivity	[CatalystActivity:573387] histone H3K9 methyltransferase activity of Ttf-I:rDNA:CSB:G9a:NuRD [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9643592] histone methyltransferase activity (H3-K9 specific) of Ttf-I:rDNA:CSB:G9a:NuRD [nucleoplasm] Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:573322] May, B, 2010-04-10
edited	[InstanceEdit:565730] May, B, 2010-04-06
input	[SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [Complex:573377] Nucleosome [nucleoplasm] [Mus musculus] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm]
isChimeric	TRUE
literatureReference	[LiteratureReference:427448] Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a [LiteratureReference:5096460] The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions
modified	[InstanceEdit:580595] May, B, 2010-04-11 [InstanceEdit:2876561] May, B, 2012-12-23 [InstanceEdit:5219089] May, B, 2013-12-22 [InstanceEdit:5227039] May, B, 2014-01-09 [InstanceEdit:5251383] May, B, 2014-02-03 [InstanceEdit:6791249] Matthews, Lisa, 2015-08-19 [InstanceEdit:8856905] May, Bruce, 2016-02-12 [InstanceEdit:8936028] May, Bruce, 2016-08-16 [InstanceEdit:8936036] May, Bruce, 2016-08-16 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ttf-I:rRNA Promoter:Ercc6:Ehmt2 complex dimethylates histone H3 at lysine-9
output	[SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [Complex:573397] Nucleosome (deacetylated H4, H3K9me2) [nucleoplasm] [Mus musculus] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm]
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8856904] Iben, Sebastian, 2016-02-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:8860891] R-NUL-573373.4
summation	[Summation:580599] Ehmt2 (histone methyltransferase G9a) dimethylates histone H...
(inferredFrom)	[Reaction:427336] TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9 [Homo sapiens]
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No pathways have been reviewed or authored by Ttf-I:rRNA Promoter:Ercc6:Ehmt2 complex dimethylates histone H3 at lysine-9 (573373)