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Details on Person CASP9(1-416) [cytosol]

Class:Id	EntityWithAccessionedSequence:57033
_displayName	CASP9(1-416) [cytosol]
_timestamp	2013-05-03 18:44:21
compartment	[Compartment:70101] cytosol
endCoordinate	416
modified	[InstanceEdit:113604] Schmidt, EE, 2004-06-09 05:34:08 [InstanceEdit:114238] Matthews, L, 2004-06-30 20:00:00 [InstanceEdit:3211600] Jupe, S, 2013-03-07 [InstanceEdit:3322333] Wu, G, 2013-05-03 [InstanceEdit:3322334] Wu, G, 2013-05-03
name	CASP9(1-416) Caspase-9 precursor CASP-9 ICE-like apoptotic protease 6 ICE-LAP6 Apoptotic protease Mch-6 Apoptotic protease activating factor 3 APAF-3
referenceEntity	[ReferenceGeneProduct:57034] UniProt:P55211 CASP9 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:365983] R-HSA-57033.1
startCoordinate	1
(activeUnit)	[CatalystActivity:266291] cysteine-type endopeptidase activity of APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol]
(hasCandidate)	[CandidateSet:622416] Long prodomain caspases [cytosol] [Homo sapiens]
(hasComponent)	[Complex:114255] Cytochrome C:Apaf-1:ATP:Procaspase-9 [cytosol] [Homo sapiens] [Complex:6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] [Homo sapiens] [Complex:6804623] CASP9(1-416) dimer [cytosol] [Homo sapiens] [Complex:6805422] CASP9:CARD [cytosol] [Homo sapiens]
(input)	[Reaction:114256] CYCS:APAF1 binds procaspase-9 [Homo sapiens] [Reaction:198621] AKT phosphorylates caspase-9 [Homo sapiens] [Reaction:2399985] AKT1 E17K mutant phosphorylates caspase-9 [Homo sapiens] [Reaction:6805426] CARD8 binds CASP9(1-416) [Homo sapiens]
(replacementInstances)	[_Deleted:9763927] Deletion of instance: 114257
(updatedInstance)	[_UpdateTracker:9885488] Update Tracker - [EntityWithAccessionedSequence:57033] CASP9(1-416) [cytosol] - v45:[addName, modifyEndCoordinate]
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No pathways have been reviewed or authored by CASP9(1-416) [cytosol] (57033)