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Details on Person RNase P cleaves the 5' end of pre-tRNA
Class:Id Reaction:5696810
_displayName RNase P cleaves the 5' end of pre-tRNA
_doRelease TRUE
_timestamp 2015-10-24 03:37:54
authored [InstanceEdit:5696808] May, Bruce, 2015-05-29
catalystActivity [CatalystActivity:5696811] ribonuclease P activity of RNase P [nucleoplasm]
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:5696805] May, Bruce, 2015-05-30
edited [InstanceEdit:5696808] May, Bruce, 2015-05-29
goBiologicalProcess [GO_BiologicalProcess:601] tRNA 5'-leader removal
input [DefinedSet:6784574] pre-tRNA [nucleoplasm] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:5696737] Specific RNA-cleaving activities from HeLa cells [LiteratureReference:5696688] Identification and characterization of an RNA molecule that copurifies with RNase P activity from HeLa cells [LiteratureReference:5696701] Substrate recognition by human RNase P: identification of small, model substrates for the enzyme [LiteratureReference:5696734] Human mitochondrial tRNA processing [LiteratureReference:5696703] Human ribonuclease P: subunits, function, and intranuclear localization [LiteratureReference:5696686] Protein-RNA interactions in the subunits of human nuclear RNase P [LiteratureReference:6785491] RNA binding properties of conserved protein subunits of human RNase P [LiteratureReference:5696697] Localization in the nucleolus and coiled bodies of protein subunits of the ribonucleoprotein ribonuclease P [LiteratureReference:6785710] RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme
modified [InstanceEdit:6784528] May, Bruce, 2015-06-20 [InstanceEdit:6784590] May, Bruce, 2015-06-21 [InstanceEdit:6785493] May, Bruce, 2015-06-29 [InstanceEdit:6787743] May, Bruce, 2015-07-16 [InstanceEdit:6790486] May, Bruce, 2015-08-10 [InstanceEdit:6790493] May, Bruce, 2015-08-10 [InstanceEdit:6792692] May, Bruce, 2015-08-25 [InstanceEdit:6806694] May, Bruce, 2015-10-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name RNase P cleaves the 5' end of pre-tRNA
output [DefinedSet:6784537] 5' cleaved pre-tRNA [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate 2015-09-22
releaseStatus NEW
reviewed [InstanceEdit:6790491] Levinger, Louis, 2015-08-10 [InstanceEdit:6792690] Motorin, Yuri, 2015-08-25 [InstanceEdit:6806693] Jarrous, Nayef, 2015-10-24
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:6796911] R-HSA-5696810.3
summation [Summation:6784584] The RNase P RNA-protein complex located in the nucleus endon...
(hasEvent) [Pathway:6784531] tRNA processing in the nucleus [Homo sapiens]
(precedingEvent) [Reaction:5696815] ELAC2 cleaves the 3' end of pre-tRNA [Homo sapiens]
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