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Details on Person Loss of SAR1B GTPase

Class:Id	Reaction:5694527
_displayName	Loss of SAR1B GTPase
_doRelease	TRUE
_timestamp	2015-09-04 20:35:30
authored	[InstanceEdit:199976] Gillespie, ME, 2007-07-13 20:42:29
catalystActivity	[CatalystActivity:5694526] GTPase activity of COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane]
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:5694528] Rothfels, Karen, 2015-05-21
edited	[InstanceEdit:203980] Gillespie, ME, 2007-11-21 20:48:45
input	[Complex:5694523] COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] [Homo sapiens]
literatureReference	[LiteratureReference:204031] COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites [LiteratureReference:204034] Dynamics of transitional endoplasmic reticulum sites in vertebrate cells [LiteratureReference:211507] Mechanisms of COPII vesicle formation and protein sorting
modified	[InstanceEdit:6792715] Rothfels, Karen, 2015-08-25 [InstanceEdit:6793105] Rothfels, Karen, 2015-08-30 [InstanceEdit:6793574] Rothfels, Karen, 2015-09-01 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Loss of SAR1B GTPase
output	[Complex:203989] SAR1B:GDP [cytosol] [Homo sapiens] [SimpleEntity:29372] Pi [cytosol] [Complex:203975] SEC23:SEC24 [cytosol] [Homo sapiens] [DefinedSet:5694244] COPII cargo:receptors [endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent	[Reaction:5694522] Inner coat assembly and cargo binding [Homo sapiens] [Reaction:203977] SAR1 Activation And Membrane Binding [Homo sapiens]
releaseDate	2015-09-22
releaseStatus	NEW
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796874] R-HSA-5694527.2
summation	[Summation:204027] Sar1p-GTP hydrolysis is increased 15-30-fold by Sec23p. Sar1...
(hasEvent)	[Pathway:204005] COPII-mediated vesicle transport [Homo sapiens]
(inferredFrom)	[Reaction:1113220] Loss of Sar1p GTPase [Oryza sativa]
(precedingEvent)	[Reaction:203977] SAR1 Activation And Membrane Binding [Homo sapiens]
(replacementInstances)	[_Deleted:6792802] Deletion of instance: 203996
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No pathways have been reviewed or authored by Loss of SAR1B GTPase (5694527)