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Details on Person A4GNT transfers GlcNAc to core 2 mucins

Class:Id	Reaction:5694487
_displayName	A4GNT transfers GlcNAc to core 2 mucins
_doRelease	TRUE
_timestamp	2025-03-18 08:56:11
authored	[InstanceEdit:5694479] Jassal, Bijay, 2015-05-21
catalystActivity	[CatalystActivity:5694504] acetylglucosaminyltransferase activity of A4GNT [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:5694479] Jassal, Bijay, 2015-05-21
edited	[InstanceEdit:5694479] Jassal, Bijay, 2015-05-21
input	[DefinedSet:1462066] Core 2 mucins [Golgi lumen] [Homo sapiens] [SimpleEntity:914003] UDP-GlcNAc [Golgi lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:5694469] Expression cloning of a human alpha1, 4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1-->4Galbeta-->R, a glycan specifically expressed in the gastric gland mucous cell-type mucin [LiteratureReference:5694477] Immunohistochemical demonstration of alpha1,4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1,4Galbeta residues in human gastrointestinal mucosa
modified	[InstanceEdit:6784185] Jassal, Bijay, 2015-06-18 [InstanceEdit:6784297] Jassal, Bijay, 2015-06-19 [InstanceEdit:6784940] Jassal, Bijay, 2015-06-23 [InstanceEdit:6785140] Jassal, Bijay, 2015-06-25 [InstanceEdit:6785240] Jassal, Bijay, 2015-06-26 [InstanceEdit:6792911] Jassal, Bijay, 2015-08-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9942597] Stephan, Ralf, 2025-03-18
name	A4GNT transfers GlcNAc to core 2 mucins
output	[DefinedSet:6784268] Core 2a mucins [Golgi lumen] [Homo sapiens] [SimpleEntity:205687] UDP [Golgi lumen]
precedingEvent	[Reaction:914012] GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins [Homo sapiens] [Reaction:1964505] C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) [Homo sapiens]
releaseDate	2015-09-22
releaseStatus	NEW
reviewed	[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796871] R-HSA-5694487.3
summation	[Summation:5694450] Alpha-1,4-N-acetylglucosaminyltransferase (A4GNT) can cataly...
(hasEvent)	[Pathway:913709] O-linked glycosylation of mucins [Homo sapiens]
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No pathways have been reviewed or authored by A4GNT transfers GlcNAc to core 2 mucins (5694487)