Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person NSF ATPase activity dissociates cis-SNARE

Class:Id	Reaction:5694425
_displayName	NSF ATPase activity dissociates cis-SNARE
_doRelease	TRUE
_timestamp	2015-11-03 16:01:07
authored	[InstanceEdit:5688242] Rothfels, Karen, 2015-04-14
catalystActivity	[CatalystActivity:5694354] ATP hydrolysis activity of cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane]
compartment	[Compartment:6791047] endoplasmic reticulum-Golgi intermediate compartment membrane
created	[InstanceEdit:5694424] Rothfels, Karen, 2015-05-21
edited	[InstanceEdit:5688570] Rothfels, Karen, 2015-04-17
input	[Complex:5694312] cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5688473] Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles [LiteratureReference:5688485] An NSF function distinct from ATPase-dependent SNARE disassembly is essential for Golgi membrane fusion [LiteratureReference:5688502] Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion [LiteratureReference:5688488] Assembly and disassembly of a ternary complex of synaptobrevin, syntaxin, and SNAP-25 in the membrane of synaptic vesicles [LiteratureReference:5688492] Multiple binding proteins suggest diverse functions for the N-ethylmaleimide sensitive factor [LiteratureReference:5688493] NSF N-terminal domain crystal structure: models of NSF function [LiteratureReference:5688498] Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF) [LiteratureReference:5688507] Three ?SNAP and 10 ATP molecules are used in SNARE complex disassembly by N-ethylmaleimide-sensitive factor (NSF) [LiteratureReference:5688193] Membrane fusion: grappling with SNARE and SM proteins
modified	[InstanceEdit:5694513] Rothfels, Karen, 2015-05-21 [InstanceEdit:6791049] Gillespie, Marc E, 2015-08-17 [InstanceEdit:6791091] Rothfels, Karen, 2015-08-19 [InstanceEdit:6792566] Rothfels, Karen, 2015-08-25 [InstanceEdit:6807863] Rothfels, Karen, 2015-11-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NSF ATPase activity dissociates cis-SNARE
output	[SimpleEntity:29372] Pi [cytosol] [CandidateSet:5694313] SNAPs [cytosol] [Homo sapiens] [CandidateSet:5694313] SNAPs [cytosol] [Homo sapiens] [CandidateSet:5694313] SNAPs [cytosol] [Homo sapiens] [CandidateSet:5694306] ER-to-ERGIC v-SNARES [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens] [EntityWithAccessionedSequence:5688142] BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens] [EntityWithAccessionedSequence:535472] GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens] [EntityWithAccessionedSequence:5688147] SCFD1 [cytosol] [Homo sapiens] [Complex:2193131] NSF hexamer [cytosol] [Homo sapiens] [CandidateSet:6807784] STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] [Homo sapiens]
precedingEvent	[Reaction:5694423] NSF and SNAPs bind cis-SNARE complex [Homo sapiens] [Reaction:5694446] BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle [Homo sapiens]
releaseDate	2015-09-22
releaseStatus	NEW
reviewed	[InstanceEdit:6791049] Gillespie, Marc E, 2015-08-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796857] R-HSA-5694425.3
summation	[Summation:5694378] NSF-dependent hydrolysis of ATP is required to disassociate ...
(hasEvent)	[Pathway:204005] COPII-mediated vesicle transport [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783960] Update Tracker - [Reaction:5694425] NSF ATPase activity dissociates cis-SNARE - v55:[add_removeOutput, modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by NSF ATPase activity dissociates cis-SNARE (5694425)