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Details on Person DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate

Class:IdReaction:5694018
_displayNameDLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate
_doReleaseTRUE
_timestamp2015-09-04 20:35:01
authored[InstanceEdit:5694021] Jassal, Bijay, 2015-05-20
catalystActivity[CatalystActivity:5694028] dihydrolipoyl dehydrogenase (NADH) activity of OGDH complex [mitochondrial matrix]
compartment[Compartment:5460] mitochondrial matrix
created[InstanceEdit:5694021] Jassal, Bijay, 2015-05-20
edited[InstanceEdit:5694021] Jassal, Bijay, 2015-05-20
input[Complex:5693982] GCSH:DHLL [mitochondrial matrix] [Homo sapiens]
[SimpleEntity:113526] NAD+ [mitochondrial matrix]
isChimericFALSE
literatureReference[LiteratureReference:70060] Dihydrolipoamide dehydrogenase-binding protein of the human pyruvate dehydrogenase complex. DNA-derived amino acid sequence, expression, and reconstitution of the pyruvate dehydrogenase complex
[LiteratureReference:5694026] How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complex
modified[InstanceEdit:6783986] Jassal, Bijay, 2015-06-18
[InstanceEdit:6784944] Jassal, Bijay, 2015-06-23
[InstanceEdit:6785240] Jassal, Bijay, 2015-06-26
[InstanceEdit:6792577] Jassal, Bijay, 2015-08-25
[InstanceEdit:6792911] Jassal, Bijay, 2015-08-28
[InstanceEdit:6793630] Jassal, Bijay, 2015-09-02
[InstanceEdit:6793635] Jassal, Bijay, 2015-09-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate
output[EntityWithAccessionedSequence:6793611] Lipo-K107-GCSH [mitochondrial matrix] [Homo sapiens]
[SimpleEntity:113529] H+ [mitochondrial matrix]
[SimpleEntity:29362] NADH [mitochondrial matrix]
precedingEvent
releaseDate2015-09-22
releaseStatusNEW
reviewed[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6796842] R-HSA-5694018.2
summation[Summation:5694019] The last step in the glycine cleavage system is the reoxidat...
(hasEvent)[Pathway:6783984] Glycine degradation [Homo sapiens]
(precedingEvent)[Reaction:5693967] PXLP-K754-GLDC dimer decarboxylates Gly [Homo sapiens]
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