Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person AMT transfers NH2CH2 from GCSH:SAMDLL to THF

Class:Id	Reaction:5693977
_displayName	AMT transfers NH2CH2 from GCSH:SAMDLL to THF
_doRelease	TRUE
_timestamp	2025-02-25 22:16:25
authored	[InstanceEdit:5693975] Jassal, Bijay, 2015-05-19
catalystActivity	[CatalystActivity:5693980] aminomethyltransferase activity of AMT [mitochondrial matrix]
catalystActivityReference	[CatalystActivityReference:9930740] aminomethyltransferase activity of AMT [mitochondrial matrix] Crystal structure of human T-protein of glycine cleavage system at 2.0 A resolution and its implication for understanding non-ketotic hyperglycinemia
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:5693975] Jassal, Bijay, 2015-05-19
crossReference	[DatabaseIdentifier:9930731] RHEA:16946
edited	[InstanceEdit:5693975] Jassal, Bijay, 2015-05-19
input	[Complex:5693969] AmMeLipoGCSH:SAMDLL [mitochondrial matrix] [Homo sapiens] [SimpleEntity:200671] THF [mitochondrial matrix]
internalReviewed	[InstanceEdit:9930750] D'Eustachio, Peter, 2024-12-05
isChimeric	FALSE
literatureReference	[LiteratureReference:5693986] Mechanism of the glycine cleavage reaction. Further characterization of the intermediate attached to H-protein and of the reaction catalyzed by T-protein [LiteratureReference:9930733] Crystal structure of human T-protein of glycine cleavage system at 2.0 A resolution and its implication for understanding non-ketotic hyperglycinemia
modified	[InstanceEdit:5693985] Jassal, Bijay, 2015-05-19 [InstanceEdit:5694021] Jassal, Bijay, 2015-05-20 [InstanceEdit:6783986] Jassal, Bijay, 2015-06-18 [InstanceEdit:6784943] Jassal, Bijay, 2015-06-23 [InstanceEdit:6785240] Jassal, Bijay, 2015-06-26 [InstanceEdit:6792911] Jassal, Bijay, 2015-08-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9930741] D'Eustachio, Peter, 2024-12-05 [InstanceEdit:9930749] D'Eustachio, Peter, 2024-12-06 [InstanceEdit:9939374] D'Eustachio, Peter, 2025-02-25
name	AMT transfers NH2CH2 from GCSH:SAMDLL to THF (6S)-5,6,7,8-tetrahydrofolate + N(6)-((R)-S(8)-aminomethyldihydrolipoyl)-L-lysyl-(protein) => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + N(6)-((R)-dihydrolipoyl)-L-lysyl-(protein) + NH4(+) AMT degrades GCSH:SAMDLL to GCSH:DHLL
output	[Complex:5693982] GCSH:DHLL [mitochondrial matrix] [Homo sapiens] [SimpleEntity:5693984] 5,10-methylene-THF [mitochondrial matrix] [SimpleEntity:113561] NH4+ [mitochondrial matrix]
precedingEvent	[Reaction:5693967] PXLP-K754-GLDC dimer decarboxylates Gly [Homo sapiens] [Reaction:5694018] DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate [Homo sapiens] [Reaction:904864] Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2015-09-22
releaseStatus	NEW
reviewed	[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26 [InstanceEdit:9939375] Hill, David P, 2025-02-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796841] R-HSA-5693977.3
structureModified	[InstanceEdit:9930741] D'Eustachio, Peter, 2024-12-05
summation	[Summation:5693987] The major degradative pathway for the amino acid glycine is ...
(hasEvent)	[Pathway:6783984] Glycine degradation [Homo sapiens]
(precedingEvent)	[Reaction:5694018] DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9939730] Update Tracker - [Reaction:5693977] AMT transfers NH2CH2 from GCSH:SAMDLL to THF - v92:[add_removeOutput, removeLiteratureReference]
[Change default viewing format]

No pathways have been reviewed or authored by AMT transfers NH2CH2 from GCSH:SAMDLL to THF (5693977)