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Query author contributions in Reactome

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Details on Person ATM phosphorylates NBN

Class:IdReaction:5693598
_displayNameATM phosphorylates NBN
_doReleaseTRUE
_timestamp2022-09-13 18:04:00
authored[InstanceEdit:83535] Matthews, L, 2003-11-18 00:00:00
catalystActivity[CatalystActivity:5682167] protein serine/threonine kinase activity of DNA DSBs:MRN:p-S1981,Ac-K3016-ATM:KAT5 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5693618] Orlic-Milacic, Marija, 2015-05-16
edited[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
input[SimpleEntity:29358] ATP [nucleoplasm]
[Complex:5682055] DNA DSBs:MRN:p-S1981,Ac-K3016-ATM:KAT5 [nucleoplasm] [Homo sapiens]
literatureReference[LiteratureReference:5682163] ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway
[LiteratureReference:5682158] ATM-dependent phosphorylation of nibrin in response to radiation exposure
[LiteratureReference:5682146] Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
[LiteratureReference:83554] A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.
modified[InstanceEdit:5693622] Orlic-Milacic, Marija, 2015-05-16
[InstanceEdit:6784748] Orlic-Milacic, Marija, 2015-06-22
[InstanceEdit:6792494] Orlic-Milacic, Marija, 2015-08-24
[InstanceEdit:6792791] Orlic-Milacic, Marija, 2015-08-27
[InstanceEdit:9816782] Orlic-Milacic, Marija, 2022-09-13
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameATM phosphorylates NBN
output[SimpleEntity:113582] ADP [nucleoplasm]
[Complex:5682162] DNA DSB:p-MRN:p-S1981,Ac-K3016-ATM:KAT5 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2003-11-03
reviewed[InstanceEdit:5693179] Borowiec, James A, 2015-06-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:6796822] R-HSA-5693598.3
summation[Summation:5693550] NSB1 (NBN) is a component of the MRN (MRE11:RAD50:NBN) compl...
(hasEvent)[Pathway:5693565] Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks [Homo sapiens]
(precedingEvent)[Reaction:5693602] ATM recognizes H2AFX-Nucleosomes [Homo sapiens]
(replacementInstances)[_Deleted:6793158] Deletion of instance: 75241
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