Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Association of RAD51 with RAD52:DNA double-strand break ends

Class:Id	Reaction:5693564
_displayName	Association of RAD51 with RAD52:DNA double-strand break ends
_doRelease	TRUE
_timestamp	2022-02-24 17:10:04
authored	[InstanceEdit:83604] Matthews, L, 2003-11-23 12:20:00
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5693618] Orlic-Milacic, Marija, 2015-05-16
edited	[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
input	[EntityWithAccessionedSequence:62637] RAD51 [nucleoplasm] [Homo sapiens] [Complex:5693547] p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:83614] Heteroduplex formation by human Rad51 protein: effects of DNA end-structure, hRP-A and hRad52. [LiteratureReference:83613] Visualisation of human rad52 protein and its complexes with hRad51 and DNA. [LiteratureReference:5686569] Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks [LiteratureReference:5686553] Genetic steps of mammalian homologous repair with distinct mutagenic consequences [LiteratureReference:217133] Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl [LiteratureReference:5686535] Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding [LiteratureReference:109575] Structure of the single-strand annealing domain of human RAD52 protein.
modified	[InstanceEdit:5693622] Orlic-Milacic, Marija, 2015-05-16 [InstanceEdit:6784748] Orlic-Milacic, Marija, 2015-06-22 [InstanceEdit:6784817] Orlic-Milacic, Marija, 2015-06-22 [InstanceEdit:6792494] Orlic-Milacic, Marija, 2015-08-24 [InstanceEdit:9766963] Orlic-Milacic, Marija, 2022-02-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Association of RAD51 with RAD52:DNA double-strand break ends
negativePrecedingEvent	[NegativePrecedingEvent:9766949] Futile Cycle: ERCC1:XPF cleaves flaps generated by SSA
output	[Complex:5693590] RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:5693580] Association of RAD52 with the RPA complex at resected DNA DSBs [Homo sapiens] [Reaction:5685156] ATR phosphorylates RPA2 [Homo sapiens] [Reaction:5686587] ABL1 phosphorylates RAD52 [Homo sapiens]
releaseDate	2003-11-03
reviewed	[InstanceEdit:5693179] Borowiec, James A, 2015-06-12
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5692524] Orlic-Milacic, Marija, 2015-05-12
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796811] R-HSA-5693564.3
summation	[Summation:5693585] RAD52 can simultaneously interact with RAD51 and RPA. The in...
(hasEvent)	[Pathway:5685938] HDR through Single Strand Annealing (SSA) [Homo sapiens]
(precedingEvent)	[Reaction:5686642] RAD52 promotes single strand annealing at resected DNA DSBs [Homo sapiens]
(replacementInstances)	[_Deleted:6793033] Deletion of instance: 83642
[Change default viewing format]

No pathways have been reviewed or authored by Association of RAD51 with RAD52:DNA double-strand break ends (5693564)