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Details on Person CRYM reduces P2C to PPCA

Class:Id	Reaction:5693347
_displayName	CRYM reduces P2C to PPCA
_doRelease	TRUE
_timestamp	2024-10-29 21:41:09
authored	[InstanceEdit:5693366] Jassal, Bijay, 2015-05-15
catalystActivity	[CatalystActivity:5693316] delta1-piperideine-2-carboxylate reductase activity of CRYM [peroxisomal matrix]
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:5693366] Jassal, Bijay, 2015-05-15
crossReference	[DatabaseIdentifier:9925989] RHEA:12526
edited	[InstanceEdit:5693366] Jassal, Bijay, 2015-05-15
input	[SimpleEntity:5693311] P2C [peroxisomal matrix] [SimpleEntity:193465] H+ [peroxisomal matrix] [SimpleEntity:113602] NADPH [peroxisomal matrix]
isChimeric	FALSE
literatureReference	[LiteratureReference:5693315] Insights into Enzyme Catalysis and Thyroid Hormone Regulation of Cerebral Ketimine Reductase/μ-Crystallin Under Physiological Conditions [LiteratureReference:5693358] Crystal structure of human micro-crystallin complexed with NADPH
modified	[InstanceEdit:6783876] Jassal, Bijay, 2015-06-17 [InstanceEdit:6785238] Jassal, Bijay, 2015-06-26 [InstanceEdit:6785240] Jassal, Bijay, 2015-06-26 [InstanceEdit:6792911] Jassal, Bijay, 2015-08-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9925993] D'Eustachio, Peter, 2024-10-29
name	CRYM reduces P2C to PPCA Delta(1)-piperideine-2-carboxylate + H(+) + NADPH => L-pipecolate + NADP(+)
output	[SimpleEntity:5693325] PPCA [peroxisomal matrix] [SimpleEntity:389556] NADP+ [peroxisomal matrix]
releaseDate	2015-09-22
releaseStatus	NEW
reviewed	[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796800] R-HSA-5693347.3
summation	[Summation:5693340] The ketimine reductase mu-crystallin protein (CRYM) is a key...
(hasEvent)	[Pathway:71064] Lysine catabolism [Homo sapiens]
(precedingEvent)	[Reaction:6783880] PIPOX oxidises PPCA to P6C [Homo sapiens]
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No pathways have been reviewed or authored by CRYM reduces P2C to PPCA (5693347)